Evidence map›Paper›PMID 40337187›Full record

ArticleJournal of patient-centered research and reviews2025

Bridging the Gap Between Knowledge and Practices Pertaining to Naloxone Use: A Single-Institution Experience in North Carolina.

Michael S Argenyi, Gisele Bailey, Christopher J McLouth, Erin Barnes, Candice J McNeil

Abstract read
In one paragraph

Article in Journal of patient-centered research and reviews, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Michael S ArgenyiDepartment of Anesthesiology, Wake Forest School of Medicine, Winston-Salem, NC.
Gisele BaileyUniversity of North Carolina Chapel Hill School of Law, Raleigh, NC.
Christopher J McLouthDepartment of Biostatistics, University of Kentucky College of Public Health, Lexington, KY.
Erin BarnesDepartment of Internal Medicine, Section on Infectious Diseases, Wake Forest School of Medicine, Winston-Salem, NC.
Candice J McNeilDepartment of Internal Medicine, Section on Infectious Diseases, Wake Forest School of Medicine, Winston-Salem, NC.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Naloxone is a life-saving medication for opioid overdose, which claims many lives annually. This study investigated provider attitudes about, beliefs about, and barriers to naloxone use to inform an increase in provider prescription of naloxone. The survey took place at a large Southern tertiary health center. An adapted REDCap survey utilizing validated questions was distributed via institutional e-mail listservs. The results (N = 181) were analyzed using descriptive and chi-square statistics. While 90.9% of the providers had heard of the strategy of prescribing naloxone to prevent overdose, only 72.1% of providers would have considered prescribing naloxone. Providers reported implementing treatment or referrals when informed about nonprescribed opioid use (49.4%), when informed about suspected opioid use disorder (50.6%), or when patients asked for opioid use treatment advice or referral (24.4%). Responses indicated that providers are aware of prescribing naloxone to prevent overdose; however, discrepancies existed between providers' knowledge and their willingness to prescribe naloxone. Providers' reluctance to prescribe is partially explained by unfamiliarity with the safety of naloxone and counseling practices surrounding the drug, as well as the belief that prescribing naloxone encourages continued nonprescribed use of opioids. To increase provider comfort, training programs surrounding the safety and counseling practices of naloxone should be implemented.

Indexed as

attitudesnaloxoneopioid useoverdoseprovider knowledge

Identifiers

PMID40337187
PMCPMC12053811

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.