ArticleIndian journal of surgical oncology2025
Expression of Peroxisome Proliferator-Activated Receptor γ in Human Colorectal Carcinoma and Its Correlation with Clinicopathological Characteristics.
Article in Indian journal of surgical oncology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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1 citing paper in PubMed.
- Repurposing Rosiglitazone Induces Apoptosis Accompanied by Impaired Antioxidant Defense in Cholangiocarcinoma Cells: Findings from Proteomic and Functional Analyses.Pharmaceuticals (Basel, Switzerland) · 2025Article
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7 authors.
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Abstract
Peroxisome proliferator activator receptor γ (PPAR γ) activation may be responsible for inhibiting the growth of cancer cell lines, and drugs that activate PPAR γ may have therapeutic benefits. Therefore, a mutation in peroxisome proliferator activator receptor γ can produce carcinogenesis. This present study aims to assess the expression of PPAR γ by immunohistochemistry in colorectal carcinoma and its correlation with clinicopathological characteristics. Most of the cases were elderly males, and pelvic pain and bleeding were the predominant symptoms. Colon carcinoma was more common than rectal carcinoma. The adenocarcinoma NOS and mucinous carcinoma were the common histological types, and 40% cases showed lymph node metastasis. The PPAR γ expression was present in 61.8% of the patients, and it showed a significant correlation with lymph node metastasis and tumor location (
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