Evidence map›Paper›PMID 40336977›Full record

ReviewPrecision radiation oncology2024

Revolutionizing cancer treatment: The role of radiopharmaceuticals in modern cancer therapy.

Treesa P Varghese, Anish John, Jithin Mathew

Abstract readReview
In one paragraph

Review in Precision radiation oncology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed.

  1. Article
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  3. Review
  4. Article
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  6. Review
  7. Article
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  9. Review
  10. Article
  11. Article
  12. Article
  13. Review
  14. The use of radiopharmaceuticals in targeted cancer therapy: a narrative review.International journal of physiology, pathophysiology and pharmacology · 2025
    Review
  15. Review
  16. Article
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Treesa P VargheseDepartment of Pharmacy Practice Yenepoya Pharmacy College & Research Centre, Yenepoya (Deemed to be University), Naringana Mangalore Karnataka India.ORCID https://orcid.org/0000-0002-8337-319X
Anish JohnDepartment of Pharmaceutics NGSM Institute of Pharmaceutical Sciences Nitte (Deemed to be University), Deralakatte Mangalore Karnataka India.ORCID https://orcid.org/0000-0003-3131-1189
Jithin MathewDepartment of Pharmaceutics NGSM Institute of Pharmaceutical Sciences Nitte (Deemed to be University), Deralakatte Mangalore Karnataka India.ORCID https://orcid.org/0000-0002-1545-4342

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Radiopharmaceutical therapy (RPT) is a precision medicine approach that involves the targeted delivery of radioactive atoms to tumor cells, representing a breakthrough strategy for cancer treatment. Radiopharmaceuticals typically consist of a small amount of radioactive material, a radionuclide, paired with a chemical that specifically targets the cell. Some radionuclides naturally target specific cells or biological processes without the need for modification. RPT is a novel cancer treatment method that offers various advantages over current traditional treatment approaches. One of the primary advantages of RPT is its ability to target cancer cells, including those in metastatic areas. Another key advantage of RPT is that radiation can be delivered systemically, locally, or physiologically to specific cells internally rather than being applied externally. Moreover, radiotracer imaging can be utilized to determine radiopharmaceutical absorption in target tissues before providing a therapeutic dose. Compared to all other cancer treatment approaches, RPT has demonstrated high efficacy with minimal toxicity. The recent approval of multiple RPT medicines by the US Food and Drug Administration highlights the tremendous potential of this treatment. This article provides a detailed review of RPT, including insights into manufacturing procedures, safety measures, and its applications in cancer therapy.

Indexed as

quality controlradiopharmaceuticalsradiopharmaceutical therapyscintigraphy

Identifiers

PMID40336977
PMCPMC11935213

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.