Evidence map›Paper›PMID 40336970›Full record

ArticleReproductive medicine and biology

Effect of embryo cryopreservation before surgery on clinical outcomes in IVF patients with endometrioma.

Nozomi Takahashi, Yuma Kawahara, Miyuki Harada, Tomoko Makabe, Gentaro Izumi, Osamu Wada-Hiraike, Yasushi Hirota, Yutaka Osuga

Abstract read
In one paragraph

Article in Reproductive medicine and biology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Nozomi TakahashiDepartment of Obstetrics and Gynecology, Faculty of Medicine The University of Tokyo Tokyo Japan.ORCID https://orcid.org/0000-0002-3685-3502
Yuma KawaharaDepartment of Obstetrics and Gynecology, Faculty of Medicine The University of Tokyo Tokyo Japan.
Miyuki HaradaDepartment of Obstetrics and Gynecology, Faculty of Medicine The University of Tokyo Tokyo Japan.
Tomoko MakabeDepartment of Obstetrics and Gynecology, Faculty of Medicine The University of Tokyo Tokyo Japan.
Gentaro IzumiDepartment of Obstetrics and Gynecology, Faculty of Medicine The University of Tokyo Tokyo Japan.
Osamu Wada-HiraikeDepartment of Obstetrics and Gynecology, Faculty of Medicine The University of Tokyo Tokyo Japan.
Yasushi HirotaDepartment of Obstetrics and Gynecology, Faculty of Medicine The University of Tokyo Tokyo Japan.ORCID https://orcid.org/0000-0003-0241-9780
Yutaka OsugaDepartment of Obstetrics and Gynecology, Faculty of Medicine The University of Tokyo Tokyo Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose: This study evaluated whether embryo cryopreservation before surgery (ECBS) improves clinical outcomes in in vitro fertilization (IVF) patients with endometrioma. Methods: This retrospective study included patients aged 28-42 years with endometrioma who underwent oocyte retrieval at our hospital from 2019 to 2022. Seventeen patients who underwent ECBS and 43 patients who underwent embryo transfer (ET) without surgery were included. Patient characteristics, reproductive outcomes, and obstetric outcomes were compared between the groups. Results: Maximum cyst size was significantly larger in the ECBS group than in the control group. The abortion rate per pregnancy was significantly lower (0% vs. 35.5%) in the ECBS group than in the control group. The ongoing pregnancy rate per case was significantly higher in the ECBS group than in the control group (88.2% vs. 58.1%), while the time to ongoing pregnancy was similar. Among patients in the ECBS group who experienced live births, 84.6% became pregnant following three or fewer ET attempts. Multivariate analysis revealed that ECBS was the only factor associated with ongoing pregnancy. The rates of perinatal complications are comparable between the groups. Conclusions: ECBS is an effective method to improve reproductive outcomes in IVF patients with endometrioma without prolonging the time to pregnancy.

Indexed as

embryo cryopreservation before surgeryembryo transferendometriomaendometriosisin vitro fertilization

Identifiers

PMID40336970
PMCPMC12056301

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.