ArticleNeurology. Clinical practice2025
Patient Perspectives on Antiseizure Medication Discontinuation: A Mixed-Methods Exploration of Risk Perception, Tolerance, and Counseling.
Article in Neurology. Clinical practice, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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Who cites it
7 citing papers in PubMed.
- Is Patience a Virtue When Withdrawing Antiseizure Medications After Epilepsy Surgery? Maybe Not.Epilepsy currents · 2026Article
- Challenges in antiseizure medication discontinuation decisions: A qualitative study of clinicians who see patients with epilepsy.Clinical neurology and neurosurgery · 2026Article
- A mixed-methods study of patient perspectives on antiseizure medication discontinuation attempts after a period of seizure-freedom.BMJ neurology open · 2026Article
- Post-stroke seizures: classification, risk prediction, and management.Frontiers in neurology · 2026Review
- Antiseizure medication discontinuation: A mixed-methods exploration of factors considered by patients when approaching decision-making.Epilepsy research · 2025Article
- Non-discontinuation of antiseizure medication in seizure-free patients with epilepsy: Reasons and predictors among neurologists and patients.Epilepsia · 2025Article
- To Take or Not to Take Antiseizure Medications: Patient-Centered Decision-Making About Discontinuation After Seizure Freedom.Neurology. Clinical practice · 2025Article
Corrections and comments
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Authors and funding
16 authors.
Funding
Abstract
Background and Objectives: Antiseizure medications (ASMs) are standard treatment for epilepsy. Yet, because ASMs can have adverse effects, guidelines suggest considering ASM withdrawal after a period of seizure freedom. We explored patients' perceived seizure risk, seizure risk tolerance, and risk counseling techniques. Methods: We interviewed adults at least one-year seizure free, seen for epilepsy across 3 academic institutions. Participants rated their own perceived seizure risks (0 "definitely would not have another seizure" to 10 "definitely would") Results: The median age (N = 32) was 46 years (interquartile range [IQR] 33-56), with a median of 3 years since their last seizure (IQR 2-11). Participants rated their two-year chance of another seizure Discussion: Participants believed that their ASMs were highly effective and were often reluctant to withdraw. Showing hypothetical seizure risks influenced decisions, and graphical risk communication tools were generally welcomed.
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Registered trials
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