Evidence map›Paper›PMID 40336878›Full record

ArticleJournal of pharmaceutical policy and practice2025

Antibiotics stewardship: prevalence, nature, and factors associated with dispensing of antibiotics without prescription among community pharmacists in Nigeria.

Okafor Ukamaka Gladys, Chukwujindu Nzube Gabriella, Folasade Olufunke Lawal, Folorunso Oluwatoyin Bukola, Victor Chikaodiri Amaechi, Okoronkwo Ngozi Augustine

Abstract read
In one paragraph

Article in Journal of pharmaceutical policy and practice, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Prescription-only medicine requests by clients: Insights from community pharmacies.Exploratory research in clinical and social pharmacy · 2026
    Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Okafor Ukamaka GladysDepartment of Global Health and Bioethics, Euclid University, Bangui, Central African Republic.ORCID https://orcid.org/0000-0002-5578-5672
Chukwujindu Nzube GabriellaOsun State Office, Pharmacy Council of Nigeria, Osogbo, Nigeria.ORCID https://orcid.org/0000-0003-4890-0019
Folasade Olufunke LawalVictory Drugs, Lagos, Nigeria.ORCID https://orcid.org/0000-0003-0384-8595
Folorunso Oluwatoyin BukolaDepartment of Clinical Pharmacy and Pharmacy Administration, Federal University Oye Ekiti, Oye Ekiti, Nigeria.ORCID https://orcid.org/0000-0003-2647-5541
Victor Chikaodiri AmaechiBPS Pharmacy, Lagos, Nigeria.ORCID https://orcid.org/0000-0001-8653-2347
Okoronkwo Ngozi AugustineDepartment of Clinical Pharmacy and Pharmacy Administration, Abia State University, Uturu, Nigeria.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Dispensing antibiotics without a prescription is common among community pharmacists in low- and middle-income countries despite its association with antibiotic resistance. This study describes the prevalence and nature of dispensing antibiotics without prescription among community pharmacists in Nigeria and its associated factors. Method: A cross-sectional study was conducted among community pharmacists in Nigeria with a validated, online, self-administered questionnaire. Reliability was assessed with Cronbach's alpha. Descriptive and inferential statistics were performed with SPSS Version 2023 at a 0.05% significance level. Result: A total of 420 community pharmacists participated in the study. The Reliability result was 0.860, implying the data collection tool's perfect internal consistency. Independent pharmacies represented 87.4% of the respondents, and most were in urban areas (71.4%). Most respondents (98.1%) dispensed antibiotics without prescription, with (84.2%) sometimes requesting laboratory investigations before dispensing antibiotics. Cephalosporin (74.8%), penicillin (70.2%), and quinolones (68.3%) were the major classes of antibiotics dispensed. The pharmacists' confidence in their clinical skills (78.8%), ability of the antibiotics to cover a broader range of microorganisms (78.0%), inability of patients to access healthcare services in other places (67.3%), emergencies (58.3%), affordability (49.0%), patients' demand (38.2%), absence of sanctions (34%), not getting prescriptions (33.1%), were the key deciding factors for the pharmacists to dispense antibiotics without prescription or substitute class of antibiotics. Factors like financial incentives, fear of losing clients, fear of expiry, competition from other pharmacies, and trust in patients' self-diagnosis were low in driving decisions to dispense antibiotics without prescriptions. Conclusion: Non-prescription dispensing of antibiotics is high among community pharmacists in Nigeria, and is related to various factors. A strategic approach, including mandatory health insurance schemes, prescription and dispensing policies, and enforcement of antimicrobial stewardship regulations by the Nigerian government, is necessary to improve ethical practice and address the irrational dispensing and use of antibiotics in Nigeria.

Indexed as

antibioticsassociated factorscommunity pharmacistsDispensingprescription

Identifiers

PMID40336878
PMCPMC12057783

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.