Evidence map›Paper›PMID 40336859›Full record

ArticleWorld journal of nuclear medicine2025

A Case Report of Neuroleukemiosis Detected on FDG PET Scan in a Patient of Mixed Phenotype Acute Leukemia Post Bone Marrow Transplantation in Remission.

Ramya Soundararajan, Archana Yadav, Anil Kumar Avs, Hemlata Jangir

Abstract readCase Reports
In one paragraph

Article in World journal of nuclear medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Ramya SoundararajanDepartment of Nuclear Medicine, Army Hosp Research and Referral, New Delhi, India.
Archana YadavDepartment of Nuclear Medicine, Army Hosp Research and Referral, New Delhi, India.
Anil Kumar AvsDepartment of Nuclear Medicine, Army Hosp Research and Referral, New Delhi, India.
Hemlata JangirDepartment of Pathology, All India Institute of Medical Sciences, New Delhi, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Neuroleukemiosis, an exceedingly rare manifestation of leukemia, is defined as peripheral nerve infiltration by leukemic cells. The typical clinical presentation is with peripheral neuropathy and/or chloromatous masses. The diagnosis of this condition is quite challenging, as symptoms usually appear in patients during remission and there are no other signs of relapse. The diagnosis is supported with electrophysiologic testing and imaging and finally established with histopathology and immunophenotyping. We present a case of multineuritis in a patient with mixed phenotype acute leukemia during remission post allogeneic hematopoietic stem cell transplant, where inflamed thickened nerves were detected on positron emission tomography/computed tomography imaging with fluorine-18 fluorodeoxyglucose. A diagnosis of neuroleukemiosis was established via biopsy and immunophenotyping. The literature is reviewed regarding this interesting and rare clinical condition.

Indexed as

18 F-FDG PET/CTacute leukemiaextramedullaryneuroleukemiosisperipheral nerve

Identifiers

PMID40336859
PMCPMC12055254

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.