Evidence map›Paper›PMID 40336751›Full record

ArticleIJU case reports2025

A Case of Secondary Extramammary Paget's Disease Surrounding a Cutaneous Ureterostoma After Recurrence of Bladder Urothelial Carcinoma.

Masahiro Mizoguchi, Ichiro Chihara, Keisuke Sano, Tomokazu Kimura, Shuya Kandori, Hiromitsu Negoro, Bryan J Mathis, Hitomi Kawai, Daisuke Matsubara, Hiroyuki Nishiyama

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Article in IJU case reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

10 authors.

Masahiro MizoguchiDepartment of Urology Institute of Medicine, University of Tsukuba Tsukuba Ibaraki Japan.ORCID https://orcid.org/0009-0000-0222-7311
Ichiro ChiharaDepartment of Urology Institute of Medicine, University of Tsukuba Tsukuba Ibaraki Japan.
Keisuke SanoDepartment of Urology Institute of Medicine, University of Tsukuba Tsukuba Ibaraki Japan.
Tomokazu KimuraDepartment of Urology Institute of Medicine, University of Tsukuba Tsukuba Ibaraki Japan.
Shuya KandoriDepartment of Urology Institute of Medicine, University of Tsukuba Tsukuba Ibaraki Japan.ORCID https://orcid.org/0000-0003-4621-8470
Hiromitsu NegoroDepartment of Urology Institute of Medicine, University of Tsukuba Tsukuba Ibaraki Japan.
Bryan J MathisDepartment of Cardiovascular Surgery Institute of Medicine, University of Tsukuba Tsukuba Ibaraki Japan.
Hitomi KawaiDepartment of Pathology Institute of Medicine, University of Tsukuba Tsukuba Ibaraki Japan.
Daisuke MatsubaraDepartment of Pathology Institute of Medicine, University of Tsukuba Tsukuba Ibaraki Japan.
Hiroyuki NishiyamaDepartment of Urology Institute of Medicine, University of Tsukuba Tsukuba Ibaraki Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Secondary extramammary Paget's disease features intraepidermal carcinoma caused by tumor invasion and migration into adjacent skin. Case Presentation: A 68-year-old man underwent radical cystectomy and bilateral cutaneous ureterostomy for bladder cancer and right ureteral cancer. Postoperative follow-up computed tomography and urine cytology at 3 years suggested right ureteral cancer recurrence. Contemporaneous erythema and bulging of the skin around the right ureterocutaneous fistula were observed, necessitating retroperitoneoscopic nephroureterectomy and peristomal skin resection. Pathology revealed urothelial carcinoma with T2 disease at the lower ureter, plus spreading cytokeratin 7+ and cytokeratin 20+ pagetoid cells clustered within the epidermis indicative of secondary Paget's disease. Conclusion: In cases of recurrent upper urothelial carcinoma after urinary diversion, patients may develop secondary extramammary Paget's disease of the skin.

Indexed as

bulgingerythemaPaget disease extramammaryureterocutaneostomyurothelial carcinoma

Identifiers

PMID40336751
PMCPMC12055229

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.