Evidence map›Paper›PMID 40336728›Full record

ArticleIJU case reports2025

Salvage Surgery Following Remarkable Tumor Shrinkage With Enfortumab Vedotin in Advanced Urothelial Carcinoma.

Keita Minami, Rei Narimatsu, Hajime Sasaki, Tatsu Tanabe, Hiroshi Tanaka

Abstract read
In one paragraph

Article in IJU case reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Keita MinamiDepartment of Kidney Transplant Surgery and Urology Sapporo City General Hospital Sapporo Hokkaido Japan.ORCID https://orcid.org/0000-0001-7339-0079
Rei NarimatsuDepartment of Kidney Transplant Surgery and Urology Sapporo City General Hospital Sapporo Hokkaido Japan.
Hajime SasakiDepartment of Kidney Transplant Surgery and Urology Sapporo City General Hospital Sapporo Hokkaido Japan.
Tatsu TanabeDepartment of Kidney Transplant Surgery and Urology Sapporo City General Hospital Sapporo Hokkaido Japan.
Hiroshi TanakaDepartment of Kidney Transplant Surgery and Urology Sapporo City General Hospital Sapporo Hokkaido Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: We report a case in which enfortumab vedotin (EV) therapy was administered as a third-line treatment for locally advanced bladder cancer (bc), enabling successful radical resection. Case Presentation: This report describes the case of a 69-year-old male patient with locally advanced bc and pelvic lymph node (LN) metastases. After the failure of first-line chemotherapy and second-line immunotherapy, the patient received EV as third-line treatment. EV therapy resulted in significant tumor reduction, enabling successful radical cystectomy and lymph node dissection (LND). The patient remained recurrence-free for 22 months post-surgery. Conclusion: EV therapy suggests that it is a promising avenue for further exploration, potentially redefining the therapeutic landscape of historically challenging cases.

Indexed as

bladdercarcinomachemotherapyradical cystectomy

Identifiers

PMID40336728
PMCPMC12055228

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.