Evidence map›Paper›PMID 40336645›Full record

ReviewPrecision radiation oncology2024

Stereotactic body radiotherapy takes on Lung Oligometastases: Latest breakthroughs.

Xin Liu, Lei Wu, Tian Guo, Zhifeng Huang, Sen Chen, ChenYang Li, Qiufang Liu, Fenggang Wang

Abstract readReview
In one paragraph

Review in Precision radiation oncology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
  2. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Xin LiuRadiation Oncology Xi'an Medical University Xi'an Shaanxi China.ORCID https://orcid.org/0009-0002-8043-3502
Lei WuDepartment of Radiotherapy Hospital Shaanxi Provincial Cancer Hospital Xi'an Shaanxi China.
Tian GuoRadiation Oncology Xi'an Medical University Xi'an Shaanxi China.
Zhifeng HuangRadiation Oncology Xi'an Medical University Xi'an Shaanxi China.
Sen ChenRadiation Oncology Xi'an Medical University Xi'an Shaanxi China.
ChenYang LiDepartment of Radiotherapy Hospital Shaanxi Provincial Cancer Hospital Xi'an Shaanxi China.
Qiufang LiuDepartment of Radiotherapy Hospital Shaanxi Provincial Cancer Hospital Xi'an Shaanxi China.
Fenggang WangDepartment of Radiotherapy Hospital Shaanxi Provincial Cancer Hospital Xi'an Shaanxi China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Lung oligometastases represent an intermediate state of cancer dissemination between localized and widespread metastases. Stereotactic body radiation therapy (SBRT) has emerged as an effective treatment option, with an efficacy comparable to that of surgical resection. This review aimed to provide a comprehensive summary of the latest advancements and controversial issues regarding SBRT for lung oligometastases. It focuses on four crucial perspectives: efficacy of SBRT, optimal patient selection criteria, technological innovations, and synergistic effects of SBRT combined with systemic therapy. Relevant clinical trials investigating SBRT for lung oligometastases have been conducted, with median 1- and 5-year local control rates of 90% and 79%, respectively. The origin of the primary tumor, size and number of lesions, and biomarker profiles were highlighted as pivotal considerations in patient selection. The precise dose delivery was enhanced using robotic SBRT and optimized dose fractionation schemes. Evidence suggests that dose escalation above 100 Gy biologically effective dose may improve tumor control. Combined immunotherapy and SBRT have demonstrated synergistic effects in prolonging progression-free survival and overall survival. This review provides valuable insights into the precise treatment of oligometastatic lung diseases using SBRT. Further multicenter randomized trials are warranted to develop definitive patient selection criteria and optimize the integration with systemic therapies.

Indexed as

lung oligometastasesstereotactic ablative radiotherapystereotactic body radiotherapy

Identifiers

PMID40336645
PMCPMC11934980

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.