ArticlePreventive medicine reports2025
Association between anemia and mortality in patients with rheumatoid arthritis: A retrospective cohort study of the National Health and nutrition examination survey (NHANES) database.
Article in Preventive medicine reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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Who cites it
6 citing papers in PubMed.
- Article
- Article
- An Updated Review on Iron Deficiency Anemia: From Epidemiology to Diagnosis, Etiology, Prevention and Treatment.Journal of blood medicine · 2026Review
- Factors associated with concurrent cardiovascular disease in patients with rheumatoid arthritis and development of machine learning models for comorbidity identification.Frontiers in cardiovascular medicine · 2026Article
- Intensive care unit admission and mortality in rheumatic diseases.Rheumatology international · 2025Review
- Prognostic role of baseline hemoglobin level for long-term mortality in newly diagnosed rheumatoid arthritis: a cohort study.Frontiers in nutrition · 2025Article
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Authors and funding
4 authors.
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Abstract
Objectives: This study aimed to investigate the impact of anemia on all-cause and cardiovascular disease (CVD) mortality in patients with rheumatoid arthritis. Methods: Data on patients with rheumatoid arthritis were extracted from the National Health and Nutrition Examination Survey (NHANES) dataset from 1999 to 2006 and 2017-2018. The associations of total anemia, ferritin, iron deficiency anemia, non‑iron deficiency anemia, and transferrin saturation with all-cause and CVD mortality were evaluated using a weighted multivariable Cox regression model, with hazard ratios (HRs) and 95 % confidence intervals (CIs) calculated. Results: Among the 848 patients included, 495 (62.09 %) survived, 353 (37.91 %) died, and 135 (13.79 %) died from CVD. Total anemia (HR = 1.64, 95 %CI: 1.13-2.39) and iron deficiency anemia (HR = 2.02, 95 %CI: 1.37-2.96) were Aassociated with an increased risk of all-cause mortality, whereas total anemia (HR = 1.76, 95 %CI: 1.02-3.04) and non‑iron deficiency anemia (HR = 2.07, 95 %CI: 1.02-4.18) were associated with a higher risk of CVD mortality. No significant associations were found between ferritin and transferrin saturation and mortality in patients with rheumatoid arthritis ( Conclusion: Iron deficiency anemia was associated with an increased risk of all-cause mortality in patients with rheumatoid arthritis, while non‑iron deficiency anemia was associated with CVD mortality.
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