Evidence map›Paper›PMID 40336514›Full record

ArticleThe annals of applied statistics2024

A PARTIALLY FUNCTIONAL LINEAR REGRESSION FRAMEWORK FOR INTEGRATING GENETIC, IMAGING, AND CLINICAL DATA.

Ting Li, Yang Yu, J S Marron, Hongtu Zhu

Abstract read
In one paragraph

Article in The annals of applied statistics, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Ting LiSchool of Statistics and Management, Shanghai University of Finance and Economics.
Yang YuDepartment of Statistics and Operations Research, University of North Carolina at Chapel Hill.
J S MarronDepartment of Statistics and Operations Research, University of North Carolina at Chapel Hill.
Hongtu ZhuDepartment of Biostatistics, University of North Carolina at Chapel Hill.

Funding

Mapping the Causal Genetic-Imaging-Clinical Pathway for Alzheimer's DiseaseRF1AG082938 · NIA · UNIV OF NORTH CAROLINA CHAPEL HILL · PI Bingxin Zhao, Hongtu Zhu · 2023 to 2026
$3.6M
NIA NIH HHS RF1 AG082938
6 · The paper itself

Abstract

This paper is motivated by the joint analysis of genetic, imaging, and clinical (GIC) data collected in the Alzheimer's Disease Neuroimaging Initiative (ADNI) study. We propose a partially functional linear regression (PFLR) framework to map high-dimensional GIC-related pathways for Alzheimer's disease (AD). We develop a joint model selection and estimation procedure by embedding imaging data in the reproducing kernel Hilbert space and imposing the

Indexed as

Clinicalgeneticsimagingnonasymptotic error boundspartially functional linear regressionsparsity

Identifiers

PMID40336514
PMCPMC12058218

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.