Evidence map›Paper›PMID 40336500›Full record

ArticlePathogens and global health

Long-term spatio-temporal trends in global rabies burden and its association with animal rabies vaccination during 1990-2019.

Zezhen Qin, Xiaohong Ma, Zhiyang Mo, Xinxuan Hu, Huijie Qin, Rui Wang, Yaye Zhao, Ping Zheng, Qiaoshan Lu, Xianyan Tang

Abstract read
In one paragraph

Article in Pathogens and global health. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

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0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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2 · The registry

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3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

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5 · Who and what money

Authors and funding

10 authors.

Zezhen QinDepartment of Epidemiology and Biostatistics, School of Public Health, Guangxi Medical University, Nanning, People's Republic of China.
Xiaohong MaDepartment of Epidemiology and Biostatistics, School of Public Health, Guangxi Medical University, Nanning, People's Republic of China.
Zhiyang MoDepartment of Epidemiology and Biostatistics, School of Public Health, Guangxi Medical University, Nanning, People's Republic of China.
Xinxuan HuDepartment of Epidemiology and Biostatistics, School of Public Health, Guangxi Medical University, Nanning, People's Republic of China.
Huijie QinDepartment of Epidemiology and Biostatistics, School of Public Health, Guangxi Medical University, Nanning, People's Republic of China.
Rui WangDepartment of Epidemiology and Biostatistics, School of Public Health, Guangxi Medical University, Nanning, People's Republic of China.
Yaye ZhaoDepartment of Epidemiology and Biostatistics, School of Public Health, Guangxi Medical University, Nanning, People's Republic of China.
Ping ZhengDepartment of Epidemiology and Biostatistics, School of Public Health, Guangxi Medical University, Nanning, People's Republic of China.
Qiaoshan LuDepartment of Epidemiology and Biostatistics, School of Public Health, Guangxi Medical University, Nanning, People's Republic of China.
Xianyan TangDepartment of Epidemiology and Biostatistics, School of Public Health, Guangxi Medical University, Nanning, People's Republic of China.ORCID 0000-0001-6448-0355

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Rabies remains a major public health issue. Yet, trends in rabies burden associated with age, period, and cohort effects remain unknown, and the association between animal rabies vaccination and rabies burden is unclear. We aimed to understand the long-term spatio-temporal trends in global rabies burden, the impacts of age, periods, and birth cohorts, and the association between animal rabies vaccination and burden. Rabies burden data were extracted from Global Burden of Disease Study 2019. We used joinpoint regression to assess temporal trends in rabies burden and age-period-cohort model to evaluate age, period, and cohort effects on rabies incidence and mortality. Animal rabies vaccination data were obtained from World Animal Health Information System. The association between the ratio of vaccinated animals and age-standardized incidence rate was explored. From 1990 to 2019, the global rabies incident cases, deaths, and disability-adjusted life years (DALYs) decreased by 43.12%, 47.20%, and 54.59%, respectively. Age-standardized rates of incidence, mortality, and DALYs declined in all socio-demographic index (SDI) regions, yet consistently remained the highest in low SDI region. The highest rabies incidence rate and mortality rate were observed in children aged 0-9 years. Population living during 1990-1994 had the highest rabies incidence and mortality risks. Countries and territories with high rabies age-standardized incidence rate generally had low ratios of vaccinated animals. Globally, rabies burden decreased over past 30 years, yet disparities in rabies burden regarding gender, age, period, cohort and SDI region existed. Targeted strategies are needed, especially in low SDI region and among children aged 0-9 years.

Indexed as

RabiesRabies VaccinesVaccinationAdolescentAdultAnimalsChildChild, PreschoolDisability-Adjusted Life YearsDogsFemaleGlobal Burden of DiseaseGlobal HealthHumansIncidenceInfantRabies Vaccinesage-period-cohort analysisage-standardized rateglobal burden of disease studyjoinpoint regressionRabies

Identifiers

PMID40336500
PMCPMC12364113

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.