Evidence map›Paper›PMID 40336166›Full record

ArticleACS applied bio materials2025

Blue-Light Photoactivated Curcumin-Loaded Chitosan Nanoparticles Prepared by Nanoprecipitation and Ionic Gelation: A Promising Approach for Antimicrobial Photodynamic Inactivation.

Lais Fernandes Aguilera, Leandro Oliveira Araujo, William Marcondes Facchinatto, Regiane Godoy Lima, Montcharles da Silva Pontes, Jhoenne Helena Vasconcelos Pulcherio, Cynthia Suzyelen Albuquerque Caires, Kleber Thiago de Oliveira, Samuel Leite de Oliveira, Anderson Rodrigues Lima Caires

Abstract read
In one paragraph

Article in ACS applied bio materials, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Lais Fernandes AguileraInstituto de Física, Universidade Federal de Mato Grosso do Sul, CP 549, 79070-900 Campo Grande, MS, Brazil.
Leandro Oliveira AraujoInstituto de Física, Universidade Federal de Mato Grosso do Sul, CP 549, 79070-900 Campo Grande, MS, Brazil.
William Marcondes FacchinattoInstituto de Física, Universidade Federal de Mato Grosso do Sul, CP 549, 79070-900 Campo Grande, MS, Brazil.ORCID 0000-0002-1846-2700
Regiane Godoy LimaInstituto de Física, Universidade Federal de Mato Grosso do Sul, CP 549, 79070-900 Campo Grande, MS, Brazil.
Montcharles da Silva PontesInstituto de Física, Universidade Federal de Mato Grosso do Sul, CP 549, 79070-900 Campo Grande, MS, Brazil.
Jhoenne Helena Vasconcelos PulcherioInstituto de Física, Universidade Federal de Mato Grosso do Sul, CP 549, 79070-900 Campo Grande, MS, Brazil.
Cynthia Suzyelen Albuquerque CairesInstituto de Física, Universidade Federal de Mato Grosso do Sul, CP 549, 79070-900 Campo Grande, MS, Brazil.
Kleber Thiago de OliveiraDepartamento de Química, Universidade Federal de São Carlos (UFSCar), Rodovia Washington Luis. km 235─SP-310, CEP 13565-905 São Carlos, SP, Brazil.ORCID 0000-0002-9131-4800
Samuel Leite de OliveiraInstituto de Física, Universidade Federal de Mato Grosso do Sul, CP 549, 79070-900 Campo Grande, MS, Brazil.ORCID 0000-0002-8616-772X
Anderson Rodrigues Lima CairesInstituto de Física, Universidade Federal de Mato Grosso do Sul, CP 549, 79070-900 Campo Grande, MS, Brazil.ORCID 0000-0002-2602-9480

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Antimicrobial photodynamic inactivation (aPDI) represents a promising alternative strategy for combating bacterial infections. This study investigates the potential of curcumin-loaded chitosan nanoparticles (CurChNPs) as novel nanoenabled photosensitizer agents for bacterial photoinactivation. CurChNPs were synthesized using an innovative dual synthesis approach by combination of nanoprecipitation and ionic gelation methods; their physicochemical properties were also characterized. The nanoparticles exhibited excellent solubility in aqueous solutions, high curcumin encapsulation efficiency (96%), and controlled release profile. Photoinactivation assays were conducted against

Indexed as

Anti-Bacterial AgentsBiocompatible MaterialsChitosanCurcuminNanoparticlesPhotosensitizing AgentsEscherichia coliGelsLightMaterials TestingMicrobial Sensitivity TestsParticle SizePhotochemotherapyReactive Oxygen SpeciesStaphylococcus aureusSurface PropertiesAnti-Bacterial AgentsBiocompatible MaterialsChitosanCurcuminGelsPhotosensitizing AgentsReactive Oxygen Speciesbacterial inactivationblue irradiationcurcumin-loaded chitosan nanoparticlenanoprecipitation and ionic gelationphotodynamic

Identifiers

PMID40336166
PMCPMC12093364

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.