Evidence map›Paper›PMID 40335977›Full record

ArticleBMC palliative care2025

Unaddressed palliative care needs of ischemic stroke patients treated with reperfusion therapies after age 80.

Greta Sahakyan, Mira Orduyan, Ani Adamyan, Karen Koshtoyan, Gurgen Hovhannisyan, Aleksandra Karapetyan, Hovhannes Manvelyan

Abstract read
In one paragraph

Article in BMC palliative care, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Greta SahakyanDepartment of Neurology, Yerevan State Medical University, Yerevan, 0025, Armenia. drgretasahakyan@gmail.com.
Mira OrduyanDepartment of Neurology, Astghik Medical Center, Yerevan, 0028, Armenia.
Ani AdamyanDepartment of Neurology, Astghik Medical Center, Yerevan, 0028, Armenia.
Karen KoshtoyanDepartment of Neurology, Yerevan State Medical University, Yerevan, 0025, Armenia.
Gurgen HovhannisyanDepartment of Neurology, Yerevan State Medical University, Yerevan, 0025, Armenia.
Aleksandra KarapetyanDepartment of Family Medicine, Yerevan State Medical University, Yerevan, 0025, Armenia.
Hovhannes ManvelyanDepartment of Neurology, Yerevan State Medical University, Yerevan, 0025, Armenia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe implementation of acute stroke care programs with dedicated multidisciplinary stroke teams has revolutionized access to care and improved survival among older adults. However, the integration of specialized palliative support within acute stroke services remains uncommon in many developing countries. This study highlights the emerging challenges faced by patients with ischemic stroke aged ≥ 80 years treated with reperfusion therapies, identifies early palliative care needs, and underscores the importance of comprehensive support in the acute setting.

methodsWe selected consecutive patients with ischemic stroke aged ≥ 80 years who received reperfusion therapies (intravenous thrombolysis or mechanical thrombectomy) at the time of stroke unit admission. Clinical and demographic data were prospectively collected and analyzed.

resultsA total of 52 patients aged ≥ 80 years received reperfusion therapies. The in-hospital mortality rate was 5/52 (9.6%). Key challenges identified during hospitalization included dysphagia in 32 patients (61.5%), dyspnea in 7 patients (13.5%), delirium in 14 patients (26.9%), and mobility impairment and/or speech disturbance in 22 patients (42.3%).

conclusionDespite the increasing use of reperfusion therapies in patients aged ≥ 80 years, symptoms requiring comprehensive support and early palliative interventions persist in the acute stroke setting. Our findings emphasize the need for early palliative assessments to address stroke-related symptoms such as dysphagia, delirium, and mobility or speech disturbances, ultimately enhancing patient comfort. Future research is necessary to better understand stroke-specific symptom burden in the aging population and to develop strategies for integrating palliative care into acute stroke management.

Indexed as

Ischemic StrokePalliative CareReperfusionAged, 80 and overFemaleHumansMaleProspective StudiesGeriatricsIschemic strokePalliative needsReperfusion therapies

Identifiers

PMID40335977
PMCPMC12057018

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.