Evidence map›Paper›PMID 40335867›Full record

ArticleJournal of community health2025

A Latent Class Analysis of COVID-19 Vaccine Attitudes and Beliefs: Results from a Community Survey Conducted Via the Chicagoland Community Engagement Alliance (CEAL) Program.

Milkie Vu, Jimin Yeom, Duy Trinh, Jane Gou, Timothy Hong, Marym Zaheeruddin, Jessica Bishop-Royse, Madison Hartstein, Bonnie Spring, David Moskowitz and 2 more

Abstract read
In one paragraph

Article in Journal of community health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Milkie VuDepartment of Preventive Medicine, Feinberg School of Medicine, Northwestern University, 680 N. Lakeshore Drive, Suite 1400, Chicago, IL, 60611, USA. milkie.vu@northwestern.edu.ORCID 0000-0003-0230-473X
Jimin YeomDepartment of Preventive Medicine, Feinberg School of Medicine, Northwestern University, 680 N. Lakeshore Drive, Suite 1400, Chicago, IL, 60611, USA.
Duy TrinhSchool of Public and International Affairs, Princeton University, Robertson Hall, Princeton, NJ, 08540, USA.ORCID 0000-0002-9282-4773
Jane GouDepartment of Preventive Medicine, Feinberg School of Medicine, Northwestern University, 680 N. Lakeshore Drive, Suite 1400, Chicago, IL, 60611, USA.
Timothy HongDepartment of Preventive Medicine, Feinberg School of Medicine, Northwestern University, 680 N. Lakeshore Drive, Suite 1400, Chicago, IL, 60611, USA.ORCID 0000-0002-9198-3115
Marym ZaheeruddinDepartment of Preventive Medicine, Feinberg School of Medicine, Northwestern University, 680 N. Lakeshore Drive, Suite 1400, Chicago, IL, 60611, USA.
Jessica Bishop-RoyseRush University Medical Center, 600 S. Paulina St., Suite 1080, Chicago, IL, 60612, USA.ORCID 0000-0003-0692-9868
Madison HartsteinNorthwestern University Clinical and Translational Sciences (NUCATS) Institute, Feinberg School of Medicine, 750 N Lake Shore Drive, 11th Floor, Chicago, IL, 60611, USA.
Bonnie SpringDepartment of Preventive Medicine, Feinberg School of Medicine, Northwestern University, 680 N. Lakeshore Drive, Suite 1400, Chicago, IL, 60611, USA.ORCID 0000-0002-3509-0865
David MoskowitzDepartment of Public Health Sciences, University of Chicago, 5841 S. Maryland Ave MC2000, Chicago, IL, 60637, USA.ORCID 0000-0001-9935-1430
Anh DoanDepartment of Preventive Medicine, Feinberg School of Medicine, Northwestern University, 680 N. Lakeshore Drive, Suite 1400, Chicago, IL, 60611, USA.ORCID 0000-0001-9295-7368
Molly MartinDepartment of Pediatrics, University of Illinois at Chicago, 840 S. Wood St, Chicago, IL, 60612, USA.

Funding

NHLBI Maternal Morbidity and Mortality (3M) Administrative Coordinating CenterOT2HL158287 · NHLBI · WESTAT, INC. · PI Chanza Baytop · 2020 to 2026
$433.8M
Northwestern University Clinical and Translational Science Institute (NUCATS)UL1TR001422 · NCATS · NORTHWESTERN UNIVERSITY AT CHICAGO · PI D'AQUILA, RICHARD · 2015 to 2023
$56.8M
Northwestern University Clinical and Translational Science Institute (NUCATS)KL2TR001424 · NCATS · NORTHWESTERN UNIVERSITY AT CHICAGO · PI SHARMA, LEENA · 2015 to 2023
$8.1M
NUCATS CTSA K12 Program at Northwestern UniversityK12TR005104 · NCATS · NORTHWESTERN UNIVERSITY AT CHICAGO · PI Leena Sharma, BETINA YANEZ · 2024 to 2026
$3.2M
Applying the Multiphase Optimization Strategy to Develop and Test a Digital Health Intervention Targeting HPV PreventionK01CA296781 · NCI · NORTHWESTERN UNIVERSITY · PI Ha Ngan Vu · 2025 to 2026
$383k
NCATS NIH HHS K12 TR005104NCATS NIH HHS K12TR005104NCATS NIH HHS KL2 TR001424NCATS NIH HHS KL2TR001424NCATS NIH HHS UL1 TR001422NCI NIH HHS K01 CA296781NHLBI NIH HHS OT2 HL158287NIH HHS OT2HL161610
6 · The paper itself

Abstract

backgroundIn the U.S., responses to the rollout of COVID-19 vaccine varied widely, with contrasting perceptions of the vaccine. We aimed to characterize distinct groups of respondents regarding COVID-19 vaccine perceptions.

methodsData came from the 2021-2023 Common Survey (n = 852), collected in Chicago using a community-based participatory approach focusing on communities with low COVID-19 vaccination. Participants answered eight questions about vaccine-related perceptions. We conducted a latent class analysis in R.

resultsThe sample included 623 female participants (73.1%), 482 Black participants (56.6%), 259 Hispanic/Latino(a) participants (30.4%), 26 Asian participants (3.1%), and 261 participants with a college degree (30.6%). In a four-class model, Class 1 (skeptic) included 153 participants (18.0%) with low confidence in vaccine safety, effectiveness, and potential to get life back to normal. Class 2 (uncertain) included 163 participants (19.1%) who mostly indicated uncertainty. Class 3 (support with concerns) included 266 participants (31.2%) who recognized many vaccine benefits but also had concerns about its rapid development and "not being studied in people like me." Class 4 (pro-vaccine) included 270 participants (31.7%) with high confidence in vaccine safety and effectiveness and social approval of vaccination. Interestingly, both the skeptic and pro-vaccine groups had somewhat similar agreement with the statement "not enough information on COVID vaccine interaction." Class assignments varied by sociodemographic characteristics. Socioeconomic hardships were associated with a lower likelihood of being in the "pro-vaccine" group.

conclusionsGiven the distinct classes of vaccine beliefs, tailored public health messaging is needed to enhance vaccine confidence and uptake.

Indexed as

COVID-19COVID-19 VaccinesHealth Knowledge, Attitudes, PracticeAdolescentAdultAgedChicagoFemaleHumansLatent Class AnalysisMaleMiddle AgedSARS-CoV-2Surveys and QuestionnairesYoung AdultCOVID-19 VaccinesCommunity-engaged researchCOVID-19 vaccineLatent class analysisVaccine attitudesVaccine perceptions

Identifiers

PMID40335867
PMCPMC12455849

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.