ArticleEuropean archives of paediatric dentistry : official journal of the European Academy of Paediatric Dentistry2025
Antibacterial effect, antiadherence, and antiacidogenicity properties of a dental varnish containing silver nanoparticles: an in vitro study.
Article in European archives of paediatric dentistry : official journal of the European Academy of Paediatric Dentistry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
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The trial behind it
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Who cites it
2 citing papers in PubMed.
- Silver Nanoparticles in Antibacterial Research: Mechanisms, Applications, and Emerging Perspectives.International journal of molecular sciences · 2026Review
- Physicochemical and antibacterial evaluation of novel nano α-TCP-AgNPs biocomposites for direct pulp-capping applications.Frontiers in oral health · 2025Article
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
aimThe aim of the present in vitro study was to synthesize and characterize green silver nanoparticles using Larrea tridentata leaf extract as a reducing and stabilizing agent and combining the nanoparticles with a commercial fluoride varnish (Fluor Protector
methodsSilver nanoparticles were synthesized by green synthesis using Larrea tridentata leaf extract as a reducing and stabilizing agent and characterized by UV-Vis spectroscopy, dynamic light scattering (DLS), and transmission electron microscopy (TEM). Minimum inhibitory and bactericidal concentrations were determined using microdiluted plates. Antibacterial activity compared using disc diffusion. Adhesion and acidogenicity tested on deciduous teeth, divided into experimental (fluoride varnish with silver nanoparticles) and control (fluoride varnish) groups. Microorganism adhesion quantified on enamel, pH readings after 24-h incubation. Analyzed using ANOVA, Tukey's test, and Mann-Whitney U.
resultsFluoride varnish with silver nanoparticles showed better antibacterial activity than nanoparticles and varnish alone. Fluoride varnish with silver nanoparticles was more effective compared to fluoride varnish in inhibiting the adhesion and pH decreases of Streptococcus mutans and Lactobacillus acidophilus on the sound enamel, with statistically significant differences (p < 0.001).
conclusionsFluoride varnish with silver nanoparticles has a good antibacterial effect for inhibiting the adhesion and production of acid being is important in the prevention and the initial stages of dental caries.
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Registered trials
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