Evidence map›Paper›PMID 40335817›Full record

ReviewGeroScience2025

Towards Precision Geromedicine in Singapore.

Jonas John Posko Amalaraj, Louis Island, Jane Yu Ying Ong, Laureen Wang, Jose Hans M Valderas, Michael Dunn, Yap Seng Chong, Johannes Meij, Andrea B Maier

Abstract readReview
In one paragraph

Review in GeroScience, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Jonas John Posko AmalarajNUS Academy for Healthy Longevity, Yong Loo Lin School of Medicine, National University of Singapore (NUS), Singapore, 117456, Singapore.
Louis IslandNUS Academy for Healthy Longevity, Yong Loo Lin School of Medicine, National University of Singapore (NUS), Singapore, 117456, Singapore.
Jane Yu Ying OngNUS Academy for Healthy Longevity, Yong Loo Lin School of Medicine, National University of Singapore (NUS), Singapore, 117456, Singapore.
Laureen WangWell Programme, Alexandra Hospital, National University Health System (NUHS), 378 Alexandra Rd, Singapore, 159964, Singapore.
Jose Hans M ValderasCentre for Research in Health Systems Performance (CRiHSP), National University of Singapore (NUS), Singapore, 117456, Singapore.
Michael DunnCentre for Biomedical Ethics, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, 117597, Singapore.
Yap Seng ChongYong Loo Lin School of Medicine, National University of Singapore, Singapore, 117597, Singapore.
Johannes MeijNUS Academy for Healthy Longevity, Yong Loo Lin School of Medicine, National University of Singapore (NUS), Singapore, 117456, Singapore.
Andrea B MaierNUS Academy for Healthy Longevity, Yong Loo Lin School of Medicine, National University of Singapore (NUS), Singapore, 117456, Singapore. a.b.maier@vu.nl.ORCID 0000-0001-7206-1724

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Since the discovery that ageing is a modifiable process in animal models, significant advancements in geroscience have led to the emergence of the field of Precision Geromedicine, which aims to optimise health and healthspan by targeting ageing-related processes. Ageing-related diseases (ARDs), accounting for 80% of Singapore's disease burden in 2019, are on the rise as the nation approaches the "super-aged" status by 2030. In response, Singapore is reshaping its healthcare system to focus on healthy ageing, as seen in the launch of the Healthier SG initiative in 2023, which empowers citizens to manage their health proactively with support from over 1800 private general practices. Additionally, Singapore is investing in geroscience to build the foundations of Precision Geromedicine, aiming to integrate gerodiagnostics and gerotherapeutics into clinical practice. Leveraging its robust healthcare system, digital infrastructure, and socio-political stability, Singapore is well-positioned to become a model for addressing ARDs amidst global demographic shifts.

Indexed as

AgingGeriatricsPrecision MedicineAgedDelivery of Health CareHealthy AgingHumansSingaporeAgeingHealthy ageingHealthy life expectancyLongevityPrimary health care

Identifiers

PMID40335817
PMCPMC12634986

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.