Evidence map›Paper›PMID 40335789›Full record

ArticleVirchows Archiv : an international journal of pathology2026

SS18::POU5F1-fused sarcoma of the parotid with divergent ganglioneuromatous differentiation-a novel manifestation of a rare tumor.

Ming Liang Oon, Bingcheng Wu, Jaslyn Jie Lin Lee, Charmaine Tan, Ju Ee Seet, Michael Michal, Fredrik Petersson

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In one paragraph

Article in Virchows Archiv : an international journal of pathology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Ming Liang OonDepartment of Pathology, National University Hospital, Singapore, Singapore. oonml29@gmail.com.ORCID http://orcid.org/0000-0003-0493-3361
Bingcheng WuDepartment of Pathology, National University Hospital, Singapore, Singapore.
Jaslyn Jie Lin LeeDepartment of Pathology, National University Hospital, Singapore, Singapore.ORCID http://orcid.org/0000-0002-8573-7268
Charmaine TanDepartment of Otolaryngology - Head & Neck Surgery, National University Hospital, Singapore, Singapore.
Ju Ee SeetDepartment of Pathology, National University Hospital, Singapore, Singapore.
Michael MichalBioptical Laboratory, Ltd, Pilsen, Czech Republic.
Fredrik PeterssonDepartment of Pathology, National University Hospital, Singapore, Singapore. fredrikpetersson@live.se.ORCID http://orcid.org/0000-0003-1571-4703

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

SS18::POU5F1-fused sarcomas are rare tumors that show an undifferentiated round cell morphology. We report for the first time a case of SS18::POU5F1-fused sarcoma occurring in the parotid gland, with a highly unusual biphasic morphology comprising of epithelioid/undifferentiated round cell component and a ganglioneuromatous component consistent with divergent differentiation. We illustrate the cytology, histomorphological, immunohistochemical profile of the tumor, and show that both components of the tumor share a common origin. We discuss the differential diagnoses of this tumor, discuss its possible histogenesis, and perform a broad review of the literature covering this uncommon tumor.

Indexed as

GanglioneuromaOncogene Proteins, FusionParotid NeoplasmsSarcomaBiomarkers, TumorCell DifferentiationDiagnosis, DifferentialFemaleHumansImmunohistochemistryMaleMiddle AgedProto-Oncogene ProteinsRepressor ProteinsBiomarkers, TumorOncogene Proteins, FusionProto-Oncogene ProteinsRepressor ProteinsSS18 protein, humanDivergent differentiationGanglioneuromaParotidSarcomaSS18::POU5F1

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.