ArticleNature neuroscience2025
Autonomic physiological coupling of the global fMRI signal.
Article in Nature neuroscience, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers.
What it found
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Who cites it
39 citing papers in PubMed.
- A non-neuronal fMRI signal: both a confound and an opportunity for insight.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2026Review
- Baseline electrophysiology versus oxidative metabolism as traits of inter-network differences in neurometabolic association.Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2026Article
- Pupil size is linked to opposite signal fluctuations between cortical BOLD and ventricular CSF.NeuroImage · 2026Article
- Article
- The dual interpretation of edge time series: Time-varying connectivity versus statistical interaction.iScience · 2026Article
- Human striatal population state dynamics.bioRxiv : the preprint server for biology · 2026Article
- Mapping the functional connectome between grey matter and white matter.Communications biology · 2026Article
- Cortical synchrony is reduced in Alzheimer's disease and relates to arousal state.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2026Article
- Categorization is 'baked' into the brain.Nature reviews. Neuroscience · 2026Review
- Reorganization of Human Brain Waves Across Diverse States of Consciousness.bioRxiv : the preprint server for biology · 2026Article
- The anterior cingulate cortex modulates pupil-linked arousal.Science advances · 2026Article
- Linking human brain functional connectivity to underlying neurotransmission.bioRxiv : the preprint server for biology · 2026Article
- Intermittent Theta-Burst Stimulation (iTBS) Modulates Abnormal Brain Activity During Emotional Arousal in Adolescent Depression: A Pilot Study.Brain topography · 2026Article
- Functional Magnetic Resonance Imaging Signal Typically Viewed as "Noise" Has Clinical Relevance in Psychiatry.Biological psychiatry global open science · 2026Article
- Convergent and selective representations of pain, appetitive processes, aversive processes, and cognitive control in the insula.Nature communications · 2026Article
- Global Signal Removal (GSR) as graph spatial filtering.bioRxiv : the preprint server for biology · 2026Article
- Transdiagnostic Profiles of BOLD Signal Variability in Autism and Schizophrenia Spectrum Disorders: Associations With Cognition and Functioning.Human brain mapping · 2026Article
- System identification and surrogate data analyses imply approximate Gaussianity and non-stationarity of resting-brain dynamics.bioRxiv : the preprint server for biology · 2026Article
- The Regulation of Vasomotor and Cardiorespiratory Pulsations Is Disrupted in Primary Central Nervous System Lymphoma: A Case-Control fMRI Study.Human brain mapping · 2026Article
- Coupling between global brain blood oxygen level-dependent activity and cerebrospinal fluid dynamics in young endurance athletes.Experimental physiology · 2026Article
Corrections and comments
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Authors and funding
14 authors.
Funding
Abstract
The brain is closely attuned to visceral signals from the body's internal environment, as evidenced by the numerous associations between neural, hemodynamic and peripheral physiological signals. Here we show that a major mode of these brain-body cofluctuations can be captured by a single spatiotemporal pattern. Across several independent samples, as well as single-echo and multi-echo functional magnetic resonance imaging (fMRI) data acquisition sequences, we identify widespread cofluctuations in the low-frequency range (0.01-0.1 Hz) between resting-state global fMRI signals, electroencephalogram (EEG) activity, and a host of peripheral autonomic signals spanning cardiovascular, pulmonary, exocrine and smooth muscle systems. The same brain-body cofluctuations observed at rest are elicited by cued deep breathing and intermittent sensory stimuli, as well as spontaneous phasic EEG events during sleep. Furthermore, we show that the spatial structure of global fMRI signals is maintained under experimental suppression of end-tidal carbon dioxide variations, suggesting that respiratory-driven fluctuations in arterial CO
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.