ArticleNature2025
Activation of lysosomal iron triggers ferroptosis in cancer.
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Article in Nature, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 155 papers.
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155citing papers in PubMed
–field-weighted citation impact
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Who cites it
155 citing papers in PubMed.
- TFEB Attenuates Silver Nanoparticle-Induced Pulmonary Ferroptosis by Preserving Lysosomal Integrity and Limiting Iron Dysregulation.Journal of applied toxicology : JAT · 2026Article
- Ferroptosis in liver biology and diseases.Hepatology communications · 2026Review
- Carbon nanoparticle-Fe (II) complex for ferroptosis therapy in refractory solid tumors: a phase I trial.Signal transduction and targeted therapy · 2026Article
- Ferroptosis in cancer: molecular mechanisms, biological roles, and therapeutic significance.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2026Review
- Cuproptosis and ferroptosis: signal pathways, diseases and therapeutic targets.Signal transduction and targeted therapy · 2026Review
- Cysteine excess triggers a mitochondrial iron-dependent cell death.Nature metabolism · 2026Article
- Nerve injury-induced protein 2 preserves lysosomal membrane integrity to suppress ferroptosis.eLife · 2026Article
- EPHA2/CD44-directed trafficking enhances endosomal leakiness and antisense therapy delivery.The Journal of cell biology · 2026Article
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- Article
- Subcellular regulation of ferroptosis: roles of individual intracellular organelles and cross talk.American journal of physiology. Cell physiology · 2026Review
- TLDc proteins: Stress-responsive nexus regulators of redox signaling, V-ATPase dynamics, and organellar crosstalk in neurodegeneration.Redox biology · 2026Review
- Mechanisms underlying propagation of ferroptotic cell death.Nature cell biology · 2026Review
- Dietary-Derived Corchorus olitorius L. Extract Suppresses KRAS-Mutant Pancreatic Cancer by Activating Ferritinophagy-Dependent Ferroptosis.Journal of food science · 2026Article
- The irony of Parkinson's disease: Converging mechanisms of redox imbalance and ferroptosis.Redox biology · 2026Review
- Cell Type-Specific Ferroptosis Regulatory Networks in the Bone Microenvironment: Implications for the Pathogenesis and Treatment of Osteoporosis.Traffic (Copenhagen, Denmark) · 2026Review
- Ferroptosis: Newly Emerged Regulator for Human Disease.MedComm · 2026Review
- Ubiquitination-dependent regulation of ferroptosis in ischemic heart and brain.Redox biology · 2026Review
- Syntaxin 12 Sustains Endosomal-Lysosomal Homeostasis and Survival in Glioblastoma Stem-Like Cells.Traffic (Copenhagen, Denmark) · 2026Article
- African swine fever virus impairs porcine alveolar macrophages bactericidal function by disrupting lysosomal acidification and cathepsin activity.PLoS pathogens · 2026Article
95 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
46 authors.
Tatiana Cañeque *Institut Curie, CNRS, INSERM, PSL Research University, Paris, France.ORCID 0000-0002-1110-0643
Leeroy Baron *Institut Curie, CNRS, INSERM, PSL Research University, Paris, France.
Sebastian Müller *Institut Curie, CNRS, INSERM, PSL Research University, Paris, France.ORCID 0000-0002-3423-5364
Alanis CarmonaDepartment of Molecular Metabolism, Harvard T. H. Chan School of Public Health, Boston, MA, USA.
Ludovic ColombeauInstitut Curie, CNRS, INSERM, PSL Research University, Paris, France.ORCID 0000-0001-5823-2603
Antoine VersiniInstitut Curie, CNRS, INSERM, PSL Research University, Paris, France.ORCID 0000-0001-9799-2701
Stéphanie SolierInstitut Curie, CNRS, INSERM, PSL Research University, Paris, France.ORCID 0000-0003-3867-4644
Christine GailletInstitut Curie, CNRS, INSERM, PSL Research University, Paris, France.ORCID 0000-0002-1208-1130
Fabien SindikubwaboInstitut Curie, CNRS, INSERM, PSL Research University, Paris, France.ORCID 0000-0002-9381-6302
Julio L SampaioInstitut Curie, CNRS, INSERM, PSL Research University, Paris, France.
Marie SabatierDepartment of Molecular Metabolism, Harvard T. H. Chan School of Public Health, Boston, MA, USA.ORCID 0000-0001-7673-4842
Eikan MishimaInstitute of Metabolism and Cell Death, Helmholtz Zentrum München, Neuherberg, Germany.ORCID 0000-0002-3706-2745
Armel Picard-BernesInstitut Curie, CNRS, INSERM, PSL Research University, Paris, France.
Laurène SyxInstitut Curie, INSERM, Mines Paris Tech, PSL Research University, Paris, France.ORCID 0009-0005-5749-0738
Nicolas ServantInstitut Curie, INSERM, Mines Paris Tech, PSL Research University, Paris, France.ORCID 0000-0003-1678-7410
Bérangère LombardInstitut Curie, PSL Research University, Paris, France.ORCID 0000-0001-9044-3662
Damarys LoewInstitut Curie, PSL Research University, Paris, France.ORCID 0000-0002-9111-8842
Jiashuo ZhengInstitute of Metabolism and Cell Death, Helmholtz Zentrum München, Neuherberg, Germany.ORCID 0000-0002-5387-1358
Bettina PronethInstitute of Metabolism and Cell Death, Helmholtz Zentrum München, Neuherberg, Germany.ORCID 0000-0002-4119-9437
Leishemba K ThoidingjamInstitut Curie, CNRS, INSERM, PSL Research University, Paris, France.
Laurence GrimaudEcole Normale Supérieure, CNRS, PSL Research University, Paris, France.ORCID 0000-0003-3904-1822
Cameron S FraserDepartment of Molecular Metabolism, Harvard T. H. Chan School of Public Health, Boston, MA, USA.ORCID 0000-0002-8180-5913
Krystina J SzyloDepartment of Molecular Metabolism, Harvard T. H. Chan School of Public Health, Boston, MA, USA.
Emma Der KazarianCRCM, CNRS, INSERM, Institut Paoli-Calmettes, Aix-Marseille University, Marseille, France.ORCID 0009-0008-5333-4799
Caroline BonnetCRCM, CNRS, INSERM, Institut Paoli-Calmettes, Aix-Marseille University, Marseille, France.
Emmanuelle Charafe-JauffretCRCM, CNRS, INSERM, Institut Paoli-Calmettes, Aix-Marseille University, Marseille, France.
Christophe GinestierCRCM, CNRS, INSERM, Institut Paoli-Calmettes, Aix-Marseille University, Marseille, France.
Patricia Santofimia-CastañoCRCM, CNRS, INSERM, Institut Paoli-Calmettes, Aix-Marseille University, Parc Scientifique et Technologique de Luminy, Marseille, France.
Matias EstarasCRCM, CNRS, INSERM, Institut Paoli-Calmettes, Aix-Marseille University, Parc Scientifique et Technologique de Luminy, Marseille, France.
Nelson DusettiCRCM, CNRS, INSERM, Institut Paoli-Calmettes, Aix-Marseille University, Parc Scientifique et Technologique de Luminy, Marseille, France.ORCID 0000-0002-6161-8483
Juan Lucio IovannaCRCM, CNRS, INSERM, Institut Paoli-Calmettes, Aix-Marseille University, Parc Scientifique et Technologique de Luminy, Marseille, France.ORCID 0000-0003-1822-2237
Antonio Sa CunhaDepartment of Digestive and Medical Oncology, Paris Saclay University and Paul-Brousse Hospital (APHP Sud), Villejuif, France.ORCID 0000-0003-4015-5368
Gabriella PittauDepartment of Digestive and Medical Oncology, Paris Saclay University and Paul-Brousse Hospital (APHP Sud), Villejuif, France.
Pascal HammelDepartment of Digestive and Medical Oncology, Paris Saclay University and Paul-Brousse Hospital (APHP Sud), Villejuif, France.
Dimitri TzanisDepartment of Surgical Oncology, Institut Curie, Paris, France.
Sylvie BonvalotDepartment of Surgical Oncology, Institut Curie, Paris, France.ORCID 0000-0001-9726-9732
Sarah WatsonDepartment of Medical Oncology, Institut Curie, INSERM, PSL Research University, Paris, France.ORCID 0000-0003-4534-8783
Vincent GandonInstitut de Chimie Moléculaire et des Matériaux d'Orsay, CNRS, Paris Saclay University, Orsay, France.ORCID 0000-0003-1108-9410
Aditya UpadhyayDepartment of Chemistry and Biomolecular Sciences, University of Ottawa, Ottawa, Ontario, Canada.
Derek A PrattDepartment of Chemistry and Biomolecular Sciences, University of Ottawa, Ottawa, Ontario, Canada.ORCID 0000-0002-7305-745X
Florêncio Porto FreitasRudolf-Virchow-Zentrum, Center for Integrative and Translational Bioimaging, Julius-Maximilians-Universität Würzburg, Würzburg, Germany.ORCID 0000-0002-0369-4488
José Pedro Friedmann AngeliRudolf-Virchow-Zentrum, Center for Integrative and Translational Bioimaging, Julius-Maximilians-Universität Würzburg, Würzburg, Germany.ORCID 0000-0001-7706-1379
Brent R StockwellDepartment of Chemistry, Columbia University, New York, NY, USA.ORCID 0000-0002-3532-3868
Marcus ConradInstitute of Metabolism and Cell Death, Helmholtz Zentrum München, Neuherberg, Germany.ORCID 0000-0003-1140-5612
Jessalyn M UbellackerDepartment of Molecular Metabolism, Harvard T. H. Chan School of Public Health, Boston, MA, USA.ORCID 0000-0002-7855-9125
Raphaël RodriguezInstitut Curie, CNRS, INSERM, PSL Research University, Paris, France. raphael.rodriguez@curie.fr.ORCID 0000-0001-7668-446X
Funding
Training Program in Molecular MetabolismT32DK128781 · NIDDK · HARVARD UNIVERSITY D/B/A HARVARD SCHOOL OF PUBLIC HEALTH · PI Sudha B Biddinger, GOKHAN S HOTAMISLIGIL · 2021 to 2026
$1.1MNIDDK NIH HHS T32 DK128781
Abstract
Iron catalyses the oxidation of lipids in biological membranes and promotes a form of cell death called ferroptosis
Indexed as
FerroptosisIronLysosomesNeoplasmsAnimalsCarbolinesCell Line, TumorFemaleHumansMaleMiceOxidation-ReductionPhospholipidsQuinoxalinesSpiro CompoundsCarbolinesIronliproxstatin-1PhospholipidsQuinoxalinesRSL3 compoundSpiro Compounds
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.