ArticleNature2025
Native nucleosomes intrinsically encode genome organization principles.
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Article in Nature, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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16citing papers in PubMed
–field-weighted citation impact
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Who cites it
16 citing papers in PubMed.
- Euchromatin forms condensed domains with short active regions on the surface.Nature genetics · 2026Article
- Origins and consequences of oncogenic 3D chromatin remodelling.Nature reviews. Cancer · 2026Review
- Physics-based nucleosome-resolution modeling of epigenetic-driven chromatin domain dynamics.Nucleic acids research · 2026Article
- Article
- SM-NucSeq, Genetic and Epigenetic Sequencing of Nucleosomes with Single-Molecule Real-Time Sequencing.Nano letters · 2026Article
- From chromosomal protein disorder to chromatin phase separation.Epigenetics & chromatin · 2026Review
- Genome-wide DNA supercoiling arises from transcription and SMC activity and mediates transcriptional negative feedback.bioRxiv : the preprint server for biology · 2026Article
- Nucleosome spacing across cell types, diseases, and ages.Nucleic acids research · 2026Review
- Selective binding of divalent cations reshapes nucleosome mechanics and unlocks histone tail dynamics.Communications biology · 2026Article
- A Scalable MNase-seq Framework for Reproducible Nucleosome Profiling across Pluripotent Stem Cell and Cardiomyocyte Models.Computational and structural biotechnology journal · 2026Article
- Gene-scale in vitro reconstitution reveals histone acetylation directly controls chromatin architecture.Science advances · 2025Article
- Polyamine homeostasisbioRxiv : the preprint server for biology · 2025Article
- Engineered histones reshape chromatin in human cells.bioRxiv : the preprint server for biology · 2025Article
- A Biophysics of Epigenetic Rejuvenation.Cells · 2025Article
- Aere perennius: how chromatin fidelity is maintained and lost in disease.NAR molecular medicine · 2025Review
- Non-disruptive 3D profiling of combinations of epigenetic marks in single cells.bioRxiv : the preprint server for biology · 2025Article
Corrections and comments
- Update of
Authors and funding
15 authors.
Sangwoo ParkDepartment of Biophysics and Biophysical Chemistry, Johns Hopkins University School of Medicine, Baltimore, MD, USA.ORCID 0000-0002-4379-4459
Raquel Merino-Urteaga *Howard Hughes Medical Institute and Program in Cellular and Molecular Medicine, Boston Children's Hospital, Boston, MA, USA.ORCID 0009-0002-9367-0435
Violetta Karwacki-Neisius *Howard Hughes Medical Institute and Program in Cellular and Molecular Medicine, Boston Children's Hospital, Boston, MA, USA.ORCID 0009-0006-6273-9814
Gustavo Ezequiel Carrizo *Department of Oncology, The Bloomberg-Kimmel Institute for Cancer Immunotherapy, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
Advait Athreya *Computational and Systems Biology Program, MIT, Cambridge, MA, USA.ORCID 0000-0001-7931-3568
Alberto Marin-GonzalezHoward Hughes Medical Institute and Program in Cellular and Molecular Medicine, Boston Children's Hospital, Boston, MA, USA.
Nils A BenningHoward Hughes Medical Institute and Program in Cellular and Molecular Medicine, Boston Children's Hospital, Boston, MA, USA.
Jonghan ParkCollege of Medicine, Yonsei University, Seoul, Republic of Korea.ORCID 0000-0003-2907-6853
Michelle M MitchenerDepartment of Chemistry, Princeton University, Princeton, NJ, USA.ORCID 0000-0001-5036-2286
Natarajan V BhanuDepartment of Biochemistry and Molecular Biophysics, Washington University School of Medicine St. Louis, St. Louis, MO, USA.
Benjamin A GarciaDepartment of Biochemistry and Molecular Biophysics, Washington University School of Medicine St. Louis, St. Louis, MO, USA.ORCID 0000-0003-3596-4750
Bin ZhangDepartment of Chemistry, MIT, Cambridge, MA, USA.ORCID 0000-0002-3685-7503
Tom W MuirDepartment of Chemistry, Princeton University, Princeton, NJ, USA.ORCID 0000-0001-9635-0344
Erika L PearceDepartment of Oncology, The Bloomberg-Kimmel Institute for Cancer Immunotherapy, Johns Hopkins University School of Medicine, Baltimore, MD, USA.ORCID 0000-0001-5592-5439
Taekjip HaDepartment of Biophysics and Biophysical Chemistry, Johns Hopkins University School of Medicine, Baltimore, MD, USA. taekjip.ha@childrens.harvard.edu.ORCID 0000-0003-2195-6258
Funding
Shared Resources Core 2: Quantitative Proteomics CoreP01CA196539 · NCI · ROCKEFELLER UNIVERSITY · PI YOUNG, MICHAEL WARREN · 2015 to 2024
$17.6MStudies of Transfer RNAR35GM122560 · NIGMS · YALE UNIVERSITY · PI SOLL, DIETER · 2017 to 2022
$5.6MViral modulation of epitranscriptomic mechanismsR01AI118891 · NIAID · WASHINGTON UNIVERSITY · PI GARCIA, BENJAMIN A, WEITZMAN, MATTHEW D. · 2015 to 2025
$5.4MGraduate Training in Computational and Systems BiologyT32GM087237 · NIGMS · MASSACHUSETTS INSTITUTE OF TECHNOLOGY · PI BURGE, CHRISTOPHER B · 2009 to 2023
$4.6MStructure, Function and Applications of InteinsR01GM086868 · NIGMS · ROCKEFELLER UNIVERSITY · PI MUIR, TOM · 2008 to 2025
$4.4MSingle Molecule Studies of Nucleic Acids RemodelingR35GM122569 · NIGMS · JOHNS HOPKINS UNIVERSITY · PI Taekjip Ha · 2017 to 2026
$3.5MChromatin Function During Transcription and DNA Repair at Single Molecule Resolutionin Living CellsU01DK127432 · NIDDK · JOHNS HOPKINS UNIVERSITY · PI HA, TAEKJIP, JOHNSON, MARGARET ELLEN · 2020 to 2024
$3.5MProbing and Perturbing Transcriptional Condensates with Multiscale Modeling and Deep LearningR35GM133580 · NIGMS · MASSACHUSETTS INSTITUTE OF TECHNOLOGY · PI Bin Zhang · 2019 to 2026
$3.1MQuantitative mass spectrometry for comprehending epigenetic mechanisms in a new underlying neurological developmental disorderR01HD106051 · NICHD · WASHINGTON UNIVERSITY · PI Benjamin A Garcia · 2022 to 2026
$2.6MThe Role of the Amino Acid Hypusine in the Maintenance and Function of Tissue-Resident MacrophagesR01AI170599 · NIAID · JOHNS HOPKINS UNIVERSITY · PI Erika L Pearce · 2023 to 2026
$2.1MInvestigating the Cellular and Biochemical Consequences of Novel OncohistonesF32GM131632 · NIGMS · PRINCETON UNIVERSITY · PI MITCHENER, MICHELLE · 2019 to 2021
$195kNCI NIH HHS P01 CA196539NIAID NIH HHS R01 AI118891NIAID NIH HHS R01 AI170599NICHD NIH HHS R01 HD106051NIDDK NIH HHS U01 DK127432NIGMS NIH HHS F32 GM131632NIGMS NIH HHS R01 GM086868NIGMS NIH HHS R35 GM122560NIGMS NIH HHS R35 GM122569NIGMS NIH HHS R35 GM133580NIGMS NIH HHS T32 GM087237
Abstract
The eukaryotic genome is packed into nucleosomes of 147 base pairs around a histone core and is organized into euchromatin and heterochromatin, corresponding to the A and B compartments, respectively
Indexed as
GenomeNucleosomesAnimalsChromatinEpigenesis, GeneticHistonesHumansMicePolyaminesPromoter Regions, GeneticStatic ElectricityChromatinHistonesNucleosomesPolyamines
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.