Evidence map›Paper›PMID 40335687›Full record

ArticleNature2025

Deep origin of eukaryotes outside Heimdallarchaeia within Asgardarchaeota.

Jiawei Zhang, Xiaoyuan Feng, Meng Li, Yang Liu, Min Liu, Li-Jun Hou, Hong-Po Dong

Abstract read
In one paragraph

Article in Nature, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.

0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

33 citing papers in PubMed.

  1. Article
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  10. Divergent evolution of the PRPS enzymes across the tree of life.bioRxiv : the preprint server for biology · 2026
    Article
  11. Article
  12. Review
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  15. Article
  16. Review
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  18. Article
  19. The archaeal roots of eukaryotic life.Proceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  20. Toward a genomic understanding of the tree of life.Molecular biology and evolution · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Jiawei ZhangState Key Laboratory of Estuarine and Coastal Research, Yangtze Delta Estuarine Wetland Ecosystem Observation and Research Station, Ministry of Education, East China Normal University, Shanghai, China.ORCID 0000-0002-9049-482X
Xiaoyuan FengArchaeal Biology Center, Synthetic Biology Research Center, Shenzhen Key Laboratory of Marine Microbiome Engineering, Key Laboratory of Marine Microbiome Engineering of Guangdong Higher Education Institutes, Institute for Advanced Study, Shenzhen University, Shenzhen, China.
Meng LiArchaeal Biology Center, Synthetic Biology Research Center, Shenzhen Key Laboratory of Marine Microbiome Engineering, Key Laboratory of Marine Microbiome Engineering of Guangdong Higher Education Institutes, Institute for Advanced Study, Shenzhen University, Shenzhen, China.ORCID 0000-0001-8675-0758
Yang LiuArchaeal Biology Center, Synthetic Biology Research Center, Shenzhen Key Laboratory of Marine Microbiome Engineering, Key Laboratory of Marine Microbiome Engineering of Guangdong Higher Education Institutes, Institute for Advanced Study, Shenzhen University, Shenzhen, China.ORCID 0000-0002-1109-0756
Min LiuKey Laboratory of Geographic Information Science, Ministry of Education, East China Normal University, Shanghai, China.ORCID 0000-0001-6515-5095
Li-Jun HouState Key Laboratory of Estuarine and Coastal Research, Yangtze Delta Estuarine Wetland Ecosystem Observation and Research Station, Ministry of Education, East China Normal University, Shanghai, China. ljhou@sklec.ecnu.edu.cn.ORCID 0000-0002-5001-1707
Hong-Po DongState Key Laboratory of Estuarine and Coastal Research, Yangtze Delta Estuarine Wetland Ecosystem Observation and Research Station, Ministry of Education, East China Normal University, Shanghai, China. hpdong@sklec.ecnu.edu.cn.ORCID 0000-0003-4940-2943

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Research on the morphology, physiology and genomics of Asgard archaea has provided valuable insights into the evolutionary history of eukaryotes

Indexed as

ArchaeaEukaryotaPhylogenyGenome, ArchaealMetagenome

Identifiers

PMID40335687
PMCPMC12222021

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.