Evidence map›Paper›PMID 40335672›Full record

ArticleNaunyn-Schmiedeberg's archives of pharmacology2025

NDUFA8 promotes cell viability and inhibits ferroptosis and cisplatin sensitivity by stabilizing Fe-S clusters in cervical cancer.

Huaguo Xiang, Junfang Sun, Lingyue Kong, Yingzhen Wang, Xiaorou Qiu, Jinting Zeng, Guo Li, Jiehong He

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Article in Naunyn-Schmiedeberg's archives of pharmacology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

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4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Huaguo XiangDepartment of Clinical Laboratory, Fuyong People's Hospital of Baoan District, 81 Defeng Road, Fuyong Street, Shenzhen, 518103, China. xhuaguo@163.com.
Junfang SunDepartment of Clinical Laboratory, Fuyong People's Hospital of Baoan District, 81 Defeng Road, Fuyong Street, Shenzhen, 518103, China.
Lingyue KongDepartment of Clinical Laboratory, Fuyong People's Hospital of Baoan District, 81 Defeng Road, Fuyong Street, Shenzhen, 518103, China.
Yingzhen WangDepartment of Clinical Laboratory, Fuyong People's Hospital of Baoan District, 81 Defeng Road, Fuyong Street, Shenzhen, 518103, China.
Xiaorou QiuDepartment of Clinical Laboratory, Fuyong People's Hospital of Baoan District, 81 Defeng Road, Fuyong Street, Shenzhen, 518103, China.
Jinting ZengDepartment of Clinical Laboratory, Fuyong People's Hospital of Baoan District, 81 Defeng Road, Fuyong Street, Shenzhen, 518103, China.
Guo LiDepartment of Clinical Laboratory, Fuyong People's Hospital of Baoan District, 81 Defeng Road, Fuyong Street, Shenzhen, 518103, China.
Jiehong HeDepartment of Clinical Laboratory, Fuyong People's Hospital of Baoan District, 81 Defeng Road, Fuyong Street, Shenzhen, 518103, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cervical cancer (CC) ranks among the primary causes of cancer fatalities in women, with cisplatin (DDP) resistance significantly impacting clinical outcomes. NADH dehydrogenase (ubiquinone) FA8 (NDUFA8) is significantly upregulated in CC tissues and correlates with lower survival rates, but its role in cisplatin sensitivity in CC is still unclear. NDUFA8 silencing inhibited CC cell viability, promoted ferroptosis, evidenced by increased Fe

Indexed as

Antineoplastic AgentsCisplatinFerroptosisIron-Sulfur ProteinsUterine Cervical NeoplasmsAnimalsCell Line, TumorCell SurvivalDrug Resistance, NeoplasmFemaleHumansMiceMice, Inbred BALB CMice, NudeAntineoplastic AgentsCisplatinIron-Sulfur ProteinsCervical cancerCisplatinFerroptosisFe-S clustersNDUFA8

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.