Trial reportScientific reports2025
Impact of pre-existing subclinical depressive symptoms on the mental health of older adults during the COVID-19-related confinements: assessment of moderating factors including meditation training.
Trial report in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02977819 (Interventional Study in Cognitively Intact Seniors Aiming to Assess the Effects of Meditation Training and Foreign Language Learning on Behavioral, Biological and Neuroimaging Measures), which is not on this map. Not yet cited in PubMed.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Interventional Study in Cognitively Intact Seniors Aiming to Assess the Effects of Meditation Training and Foreign Language Learning on Behavioral, Biological and Neuroimaging Measures
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
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Authors and funding
13 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The COVID-19 pandemic significantly challenged mental health of populations worldwide. We aimed to assess changes in mental health of cognitively unimpaired (CU) older adults with pre-existing subclinical depressive symptoms during pandemic-related confinements, and the factors that could modulate these changes. CU older adults with (DepS, n = 53) and without (NoDepS, n = 47) pre-existing subclinical depressive symptoms (defined using the Geriatric Depression Scale at baseline) from the Age-Well randomized controlled trial (NCT02977819) were included - for whom data at baseline, post-intervention visits and during the two national confinements were available. The 18-month meditation or non-native language training intervention was completed before the pandemic. DepS, compared to NoDepS, had higher levels of depressive and anxiety symptoms at all assessments, including confinements. DepS had a greater increase in anxiety than NoDepS between the two confinements, and this increase was associated with greater ruminative brooding at baseline, but was not moderated by the meditation training intervention or by meditation practice during confinements. Pre-existing subclinical depressive symptoms in older adults contribute to mental health deterioration during confinements, with rumination being the main factor involved - stressing the need to treat these symptoms.
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