Evidence map›Paper›PMID 40335627›Full record

ReviewCommunications medicine2025

Revealing sleep and pain reciprocity with wearables and machine learning.

Samsuk Kim, Jamie M Zeitzer, Sean Mackey, Beth D Darnall

Abstract readReview
In one paragraph

Review in Communications medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Samsuk KimDepartment of Anesthesiology, Perioperative and Pain Medicine, Stanford University, Palo Alto, CA, USA. samsukk@stanford.edu.ORCID 0000-0001-8893-2248
Jamie M ZeitzerDepartment of Psychiatry and Behavioral Sciences, Center for Sleep and Circadian Sciences, Stanford University, Stanford, CA, USA.ORCID 0000-0001-6174-5282
Sean MackeyDepartment of Anesthesiology, Perioperative and Pain Medicine, Stanford University, Palo Alto, CA, USA.
Beth D DarnallDepartment of Anesthesiology, Perioperative and Pain Medicine, Stanford University, Palo Alto, CA, USA.

Funding

Interdisciplinary Research Training in Pain and Substance Use DisordersT32DA035165 · NIDA · STANFORD UNIVERSITY · PI SEAN C MACKEY · 2013 to 2026
$7.2M
Research and Mentoring in Innovative Patient Oriented Pain and Opioid ScienceK24DA053564 · NIDA · STANFORD UNIVERSITY · PI Beth Denise Darnall · 2021 to 2026
$1.0M
Mentoring in Discovery and Validation of Clinical Chronic Pain BiomarkersK24NS126781 · NINDS · STANFORD UNIVERSITY · PI MACKEY, SEAN C · 2021 to 2021
$324k
NIDA NIH HHS K24 DA053564NIDA NIH HHS T32 DA035165NINDS NIH HHS K24 NS126781U.S. Department of Health & Human Services | NIH | National Institute of Neurological Disorders and Stroke (NINDS) K24NS126781U.S. Department of Health & Human Services | NIH | National Institute on Drug Abuse (NIDA) K24DA053564U.S. Department of Health & Human Services | NIH | National Institute on Drug Abuse (NIDA) T32DA035165
6 · The paper itself

Abstract

Sleep disturbance and chronic pain share a bidirectional relationship with poor sleep exacerbating pain and pain disrupting sleep. Despite the substantial burden of sleep disturbance and pain, current treatments fail to address their interplay effectively, largely due to the lack of longitudinal data capturing their complex dynamics. Traditional sleep measurement methods that could be used to quantitate daily changes in sleep, such as polysomnography, are costly and unsuitable for large-scale studies in chronic pain populations. New wearable polysomnography devices combined with machine learning algorithms offer a scalable solution, enabling comprehensive, longitudinal analyses of sleep-pain dynamics. In this Perspective, we highlight how these technologies can overcome current limitations in sleep assessment to uncover mechanisms linking sleep and pain. These tools could transform our understanding of the sleep and pain relationship and guide the development of personalized, data-driven treatments.

Identifiers

PMID40335627
PMCPMC12059155

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.