Evidence map›Paper›PMID 40335548›Full record

ArticleNature communications2025

A short intrinsically disordered region at KtrB's N-terminus facilitates allosteric regulation of K

Janina Stautz, David Griwatz, Susann Kaltwasser, Ahmad Reza Mehdipour, Sophie Ketter, Celina Thiel, Dorith Wunnicke, Marina Schrecker, Deryck J Mills, Gerhard Hummer and 2 more

Abstract read
In one paragraph

Article in Nature communications, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. A membrane insertion code for intrinsically disordered proteins.bioRxiv : the preprint server for biology · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Janina Stautz *Institute of Biochemistry, Goethe University Frankfurt, Frankfurt am Main, Germany.
David Griwatz *Institute of Biochemistry, Goethe University Frankfurt, Frankfurt am Main, Germany.ORCID http://orcid.org/0000-0002-3564-897X
Susann KaltwasserCentral Electron Microscopy Facility, Max Planck Institute of Biophysics, Frankfurt am Main, Germany.ORCID http://orcid.org/0000-0002-4112-2771
Ahmad Reza MehdipourCenter for Molecular Modeling, Ghent University, Zwijnaarde, Belgium.
Sophie KetterInstitute of Biochemistry, Goethe University Frankfurt, Frankfurt am Main, Germany.
Celina ThielInstitute of Biochemistry, Goethe University Frankfurt, Frankfurt am Main, Germany.
Dorith WunnickeInstitute of Biochemistry, Goethe University Frankfurt, Frankfurt am Main, Germany.
Marina SchreckerInstitute of Biochemistry, Goethe University Frankfurt, Frankfurt am Main, Germany.
Deryck J MillsDepartment of Structural Biology, Max Planck Institute of Biophysics, Frankfurt am Main, Germany.ORCID http://orcid.org/0000-0003-0904-1119
Gerhard HummerDepartment of Theoretical Biophysics, Max Planck Institute of Biophysics, Frankfurt am Main, Germany.ORCID http://orcid.org/0000-0001-7768-746X
Janet VonckDepartment of Structural Biology, Max Planck Institute of Biophysics, Frankfurt am Main, Germany. janet.vonck@biophys.mpg.de.ORCID http://orcid.org/0000-0001-5659-8863
Inga HäneltInstitute of Biochemistry, Goethe University Frankfurt, Frankfurt am Main, Germany. haenelt@biochem.uni-frankfurt.de.ORCID http://orcid.org/0000-0003-1495-3163

Funding

Deutsche Forschungsgemeinschaft (German Research Foundation) 450648163 (P12)Deutsche Forschungsgemeinschaft (German Research Foundation) 450648163 (P14)Deutsche Forschungsgemeinschaft (German Research Foundation) 450648163 (P4)Deutsche Forschungsgemeinschaft (German Research Foundation) CRC807Deutsche Forschungsgemeinschaft (German Research Foundation) HA6322/3-1Deutsche Forschungsgemeinschaft (German Research Foundation) HA 6322/4-1Deutsche Forschungsgemeinschaft (German Research Foundation) HA 6322/5-1
6 · The paper itself

Abstract

K

Indexed as

Bacterial ProteinsCation Transport ProteinsIntrinsically Disordered ProteinsPotassium ChannelsVibrio alginolyticusAdenosine DiphosphateAdenosine TriphosphateAllosteric RegulationCryoelectron MicroscopyIon Channel GatingModels, MolecularPotassiumProtein BindingProtein ConformationAdenosine DiphosphateAdenosine TriphosphateBacterial ProteinsCation Transport ProteinsIntrinsically Disordered ProteinsKtrB protein, BacteriaPotassiumPotassium Channels

Identifiers

PMID40335548
PMCPMC12059179

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.