Evidence map›Paper›PMID 40335455›Full record

ArticleBlood cancer journal2025

The ratio of brain to liver glucose activity and disease activity in multiple myeloma.

Sarah Dingli, Paul Rothweiler, Moritz Binder, Joselle Cook, Morie A Gertz, Suzanne Hayman, Prashant Kapoor, Taxiarchis Kourelis, Shaji K Kumar, Mustaqeem Siddiqui and 4 more

Abstract read
In one paragraph

Article in Blood cancer journal, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Diagnostic brain-to-liver [European journal of nuclear medicine and molecular imaging · 2026
    Article
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Sarah DingliEarl E. Bakken Medical Devices Center, Department of Mechanical Engineering, College of Science and Engineering, University of Minnesota, Twin Cities, MN, USA.
Paul RothweilerEarl E. Bakken Medical Devices Center, Department of Mechanical Engineering, College of Science and Engineering, University of Minnesota, Twin Cities, MN, USA.
Moritz BinderDivision of Hematology and Department of Internal Medicine, Mayo Clinic, Rochester, MN, USA.ORCID http://orcid.org/0000-0001-9014-9658
Joselle CookDivision of Hematology and Department of Internal Medicine, Mayo Clinic, Rochester, MN, USA.ORCID http://orcid.org/0000-0001-5335-9533
Morie A GertzDivision of Hematology and Department of Internal Medicine, Mayo Clinic, Rochester, MN, USA.
Suzanne HaymanDivision of Hematology and Department of Internal Medicine, Mayo Clinic, Rochester, MN, USA.
Prashant KapoorDivision of Hematology and Department of Internal Medicine, Mayo Clinic, Rochester, MN, USA.ORCID http://orcid.org/0000-0002-4342-364X
Taxiarchis KourelisDivision of Hematology and Department of Internal Medicine, Mayo Clinic, Rochester, MN, USA.ORCID http://orcid.org/0000-0001-8573-9434
Shaji K KumarDivision of Hematology and Department of Internal Medicine, Mayo Clinic, Rochester, MN, USA.ORCID http://orcid.org/0000-0001-5392-9284
Mustaqeem SiddiquiDivision of Hematology and Department of Internal Medicine, Mayo Clinic, Rochester, MN, USA.ORCID http://orcid.org/0000-0002-4640-7311
Rahma WarsameDivision of Hematology and Department of Internal Medicine, Mayo Clinic, Rochester, MN, USA.
Yi LinDivision of Hematology and Department of Internal Medicine, Mayo Clinic, Rochester, MN, USA.ORCID http://orcid.org/0000-0002-1556-6416
Arthur G ErdmanEarl E. Bakken Medical Devices Center, Department of Mechanical Engineering, College of Science and Engineering, University of Minnesota, Twin Cities, MN, USA.
David DingliDivision of Hematology and Department of Internal Medicine, Mayo Clinic, Rochester, MN, USA. dingli.david@mayo.edu.ORCID http://orcid.org/0000-0001-7477-3004

Funding

Project 4: Targeting Resistance to T-Cell Directed Therapy in Multiple MyelomaP50CA186781 · NCI · MAYO CLINIC ARIZONA · PI Peter Leif Bergsagel · 2015 to 2026
$25.5M
NCI NIH HHS P50 CA186781
6 · The paper itself

Abstract

Changes in metabolic activity in tumor cells is one of the hallmarks of cancer. Cancer cells exhibit the Warburg effect with high glucose consumption for their energy needs. This provides the basis for imaging using

Indexed as

BrainGlucoseLiverMultiple MyelomaAgedFemaleFluorodeoxyglucose F18HumansMaleMiddle AgedPositron-Emission TomographyPrognosisFluorodeoxyglucose F18Glucose

Identifiers

PMID40335455
PMCPMC12059036

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.