Evidence map›Paper›PMID 40335452›Full record

ReviewSpinal cord series and cases2025

Intramedullary spinal cord metastasis presenting as the initial manifestation of breast cancer: case report and review of the literature.

Nadia Bouattour, Sirine Sellami, Yosra Mzid, Slim Charfi, Fatma Hamza, Salma Sakka, Khaireddine Ben Mahfoudh, Amine Bahloul, Mariem Damak

Abstract readCase ReportsReview
In one paragraph

Review in Spinal cord series and cases, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Nadia BouattourDepartment of Neurology and Research Laboratory LR12SP19, Habib Bourguiba University Hospital, Sfax, Tunisia. bouattour_nadia@yahoo.fr.ORCID 0000-0001-8573-8917
Sirine SellamiDepartment of Neurology and Research Laboratory LR12SP19, Habib Bourguiba University Hospital, Sfax, Tunisia.
Yosra MzidMedical School of Sfax, University of Sfax, Sfax, Tunisia.
Slim CharfiMedical School of Sfax, University of Sfax, Sfax, Tunisia.
Fatma HamzaMedical School of Sfax, University of Sfax, Sfax, Tunisia.
Salma SakkaDepartment of Neurology and Research Laboratory LR12SP19, Habib Bourguiba University Hospital, Sfax, Tunisia.
Khaireddine Ben MahfoudhMedical School of Sfax, University of Sfax, Sfax, Tunisia.
Amine BahloulMedical School of Sfax, University of Sfax, Sfax, Tunisia.
Mariem DamakDepartment of Neurology and Research Laboratory LR12SP19, Habib Bourguiba University Hospital, Sfax, Tunisia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundIntramedullary spinal cord metastasis (ISCM) is very rare. Symptoms from ISCM metastasis being the initial presentation are extremely rare. CASE PRESENTATION: We present a case of a 42-year-old woman without previous medical history who presented with complaints of progressive lower limb weakness of three weeks evolution. Neurological examination elicited a medullary syndrome, and physical examination showed a palpable mass on her right breast. A spinal MRI revealed a dorsal intramedullary tumor mass. A biopsy sample from the breast mass revealed the diagnosis of carcinoma. The diagnosis of an Intramedullary breast cancer metastasis (IMBCM) was made according to positron emission tomography. The patient received treatment with corticosteroids and radiation therapy without improvement, and she died, 3 months after the diagnosis.

conclusionsAs far as we know, this is the first reported case of IMBCM revealing a breast carcinoma. Although extremely rare, ISCM should be considered as a differential diagnosis of a spinal intramedullary lesion.

Indexed as

Breast NeoplasmsSpinal Cord NeoplasmsAdultFatal OutcomeFemaleHumansMagnetic Resonance Imaging

Identifiers

PMID40335452
PMCPMC12059171

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.