Evidence map›Paper›PMID 40335131›Full record

ArticleBMJ open2025

Effect of tibialis anterior focal muscle vibration for gait rehabilitation in hemiplegic individuals during the subacute phase after stroke: the NEUROVIB-AVC study protocol - a multicentric randomised controlled trial.

Hugo Bessaguet, Bruno Fernandez, Vincent Malejac, Emy Nerriere, Mathias Velarde, Alexandre Coiffet, Diana Rimaud, Thomas Lapole

Registry-linked trialAbstract readClinical Trial Protocol
In one paragraph

Article in BMJ open, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05945212 (Effects of Local Vibrations Program of Dorsiflexor Muscles on Neuromotor Recovery in Subacute Stroke Patients - a Multicentric Randomized Controlled Study), which is not on this map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05945212 narecruitingnot on this map

Effects of Local Vibrations Program of Dorsiflexor Muscles on Neuromotor Recovery in Subacute Stroke Patients - a Multicentric Randomized Controlled Study

TypeinterventionalSponsorCentre Hospitalier Universitaire de Saint EtienneRan2024 to 2027Enrolled70ConditionsStroke RehabilitationArmsVibration, Sham vibration, 10 meters Walk Test, 2 Minute Walk Test (2MWT), Fugl-Meyer (FMA-LE)
3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Hugo BessaguetPhysical Medicine and Rehabilitation Department, Lyon 1, Savoie Mont-Blanc University, Inter-University Laboratory of Human Movement Biology, CHU de Saint-Étienne, Jean Monnet University, Saint-Étienne, France hugo.bessaguet@univ-st-etienne.fr.ORCID http://orcid.org/0000-0001-9731-6981
Bruno FernandezPhysical Medicine and Rehabilitation Department, Lyon 1, Savoie Mont-Blanc University, Inter-University Laboratory of Human Movement Biology, CHU de Saint-Étienne, Jean Monnet University, Saint-Étienne, France.
Vincent MalejacLyon 1, Savoie Mont-Blanc University, Inter-University Laboratory of Human Movement Biology, Jean Monnet University, Saint Priest en Jarez, France.
Emy NerriereLyon 1, Savoie Mont-Blanc University, Inter-University Laboratory of Human Movement Biology, Jean Monnet University, Saint Priest en Jarez, France.
Mathias VelardeLyon 1, Savoie Mont-Blanc University, Inter-University Laboratory of Human Movement Biology, Jean Monnet University, Saint Priest en Jarez, France.
Alexandre CoiffetLyon 1, Savoie Mont-Blanc University, Inter-University Laboratory of Human Movement Biology, Jean Monnet University, Saint Priest en Jarez, France.
Diana RimaudPhysical Medicine and Rehabilitation Department, Lyon 1, Savoie Mont-Blanc University, Inter-University Laboratory of Human Movement Biology, CHU de Saint-Étienne, Jean Monnet University, Saint-Étienne, France.
Thomas LapoleLyon 1, Savoie Mont-Blanc University, Inter-University Laboratory of Human Movement Biology, Jean Monnet University, Saint Priest en Jarez, France.ORCID http://orcid.org/0000-0002-1477-6614

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionGait recovery remains one of the most determining factors in social participation for poststroke individuals, in whom ankle dorsiflexor function is closely related to gait speed. Focal muscle vibration has shown promising neurophysiological and clinical effects in neuromotor recovery. However, it remains to be determined whether tibialis anterior focal muscle vibration applied to the paretic limb could improve walking speed when implemented in early rehabilitation after stroke occurrence. METHODS AND ANALYSIS: This study describes a multicentric randomised controlled trial in which 70 participants will be randomly assigned in a 1:1 ratio to the tibialis anterior focal muscle vibration group or the sham group, in addition to their conventional rehabilitation. Participants will receive 100 Hz vibration/sham for 30 min, five times per week, for 8 weeks. The primary outcome will be gait speed, as assessed through a 10 m walking test and will be compared between groups at the end of the intervention. Secondary outcomes will include gait abilities, neuromuscular clinical evaluations and neurophysiological measures. Outcomes will be assessed at baseline and across five visits during and after the intervention, until 16 weeks of follow-up. ETHICS AND DISSEMINATION: Ethics approval was obtained from the French Ethics Committee 'Protection des Personnes Nord Ouest III' in 30 May 2023 (IDRCB: 2023-A00489-36). The results will be published in a peer-reviewed journal and presented at scientific conferences. TRIAL REGISTRATION NUMBER: NCT05945212.

Indexed as

HemiplegiaMuscle, SkeletalStrokeStroke RehabilitationVibrationAdultAgedFemaleGaitHumansMaleMiddle AgedMulticenter Studies as TopicRandomized Controlled Trials as TopicRecovery of FunctionWalking SpeedGaitLower ExtremityNEUROPHYSIOLOGYRandomized Controlled TrialREHABILITATION MEDICINEStroke

Identifiers

PMID40335131
PMCPMC12056635

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.