Evidence map›Paper›PMID 40335108›Full record

SynthesisSaudi medical journal2025

Pocket-creation method versus conventional method of endoscopic submucosal dissection for early gastric cancer: A systematic review and meta-analysis.

Min-Min Song, Feng-Bing Wang, Jian-Lin Yang, Hai-Yan Zhang, Tai-Ping Wang

Abstract readSystematic ReviewMeta-AnalysisComparative Study
In one paragraph

Synthesis in Saudi medical journal, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Min-Min SongFrom the Department of Gastroenterology (Song, Yang, Zhang, T. Wang), The People's Hospital Of Rizhao, and from the Department of Gastrointestinal Surgery (F. Wang), Rizhao Hospital of Traditional Chinese Medicine, Rizhao, China.ORCID https://orcid.org/0009-0003-5289-0770
Feng-Bing WangFrom the Department of Gastroenterology (Song, Yang, Zhang, T. Wang), The People's Hospital Of Rizhao, and from the Department of Gastrointestinal Surgery (F. Wang), Rizhao Hospital of Traditional Chinese Medicine, Rizhao, China.
Jian-Lin YangFrom the Department of Gastroenterology (Song, Yang, Zhang, T. Wang), The People's Hospital Of Rizhao, and from the Department of Gastrointestinal Surgery (F. Wang), Rizhao Hospital of Traditional Chinese Medicine, Rizhao, China.
Hai-Yan ZhangFrom the Department of Gastroenterology (Song, Yang, Zhang, T. Wang), The People's Hospital Of Rizhao, and from the Department of Gastrointestinal Surgery (F. Wang), Rizhao Hospital of Traditional Chinese Medicine, Rizhao, China.
Tai-Ping WangFrom the Department of Gastroenterology (Song, Yang, Zhang, T. Wang), The People's Hospital Of Rizhao, and from the Department of Gastrointestinal Surgery (F. Wang), Rizhao Hospital of Traditional Chinese Medicine, Rizhao, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesTo compare the efficacy and safety between 2 endoscopic surgical approaches for early gastric cancer: pocket creation method of endoscopic submucosal dissection (PCM-ESD) and conventional ESD (CM-ESD).

methodsA comprehensive literature search was carried out in PubMed, China National Knowledge Infrastructure, and the Cochrane Library from their inception to July 2024 using medical subject headings and free-text terms, which were "pocket-creation method", "gastric cancer", "gastric neoplasms", and "endoscopic submucosal dissection" or "ESD". Two independent reviewers carried out the search, screened studies, and extracted data.

resultsA total of 578 cases were included in our study, which sourced from 2 randomized controlled trials and 5 retrospective cohort studies. Among them, 258 cases were in the intervention group that received PCM-ESD, and 320 cases were in the control group that received CM-ESD. The PCM-ESD demonstrated a significantly faster dissection speed (mean difference=5.57 mm²/min; 95% confidence interval: [4.24-6.91];

conclusionFor endoscopists, the use of PCM in early gastric cancer seems to be superior to CM-ESD in terms of dissection speed and the procedure time, and got a lower incidence of perforation. Moreover, there was no discernible difference between the 2 groups' rates of en bloc and R0 resection, and the use of PCM-ESD did not increase the chance of delayed bleeding.

Indexed as

Endoscopic Mucosal ResectionStomach NeoplasmsHumansOperative Timeendoscopic submucosal dissectionESDgastric cancersgastric neoplasmspocket-creation method

Identifiers

PMID40335108
PMCPMC12074049

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.