Evidence map›Paper›PMID 40334725›Full record

ArticleAmerican journal of ophthalmology2025

Differential Impact of Central and Global Visual Field Progression on Quality of Life in Glaucoma.

Gopikasree Gunasegaran, Sasan Moghimi, Evan Walker, Takashi Nishida, Jeffrey M Liebmann, Massimo A Fazio, Christopher A Girkin, Linda M Zangwill, Robert N Weinreb

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in American journal of ophthalmology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Gopikasree GunasegaranFrom the Viterbi Family Department of Ophthalmology (G.G., S.M., E.W., T.N., L.M.Z., and R.N.W.), Hamilton Glaucoma Center, Shiley Eye Institute, University of California San Diego, La Jolla, California, USA.
Sasan MoghimiFrom the Viterbi Family Department of Ophthalmology (G.G., S.M., E.W., T.N., L.M.Z., and R.N.W.), Hamilton Glaucoma Center, Shiley Eye Institute, University of California San Diego, La Jolla, California, USA.
Evan WalkerFrom the Viterbi Family Department of Ophthalmology (G.G., S.M., E.W., T.N., L.M.Z., and R.N.W.), Hamilton Glaucoma Center, Shiley Eye Institute, University of California San Diego, La Jolla, California, USA.
Takashi NishidaFrom the Viterbi Family Department of Ophthalmology (G.G., S.M., E.W., T.N., L.M.Z., and R.N.W.), Hamilton Glaucoma Center, Shiley Eye Institute, University of California San Diego, La Jolla, California, USA.
Jeffrey M LiebmannDepartment of Ophthalmology (J.M.L.), Bernard and Shirlee Brown Glaucoma Research Laboratory, Edward S. Harkness Eye Institute, Columbia University Medical Center, New York, New York, USA.
Massimo A FazioDepartment of Ophthalmology and Vision Sciences (M.A.F. and C.A.G.), Heersink School of Medicine, The University of Alabama at Birmingham, Birmingham, Alabama, USA.
Christopher A GirkinDepartment of Ophthalmology and Vision Sciences (M.A.F. and C.A.G.), Heersink School of Medicine, The University of Alabama at Birmingham, Birmingham, Alabama, USA.
Linda M ZangwillFrom the Viterbi Family Department of Ophthalmology (G.G., S.M., E.W., T.N., L.M.Z., and R.N.W.), Hamilton Glaucoma Center, Shiley Eye Institute, University of California San Diego, La Jolla, California, USA.
Robert N WeinrebFrom the Viterbi Family Department of Ophthalmology (G.G., S.M., E.W., T.N., L.M.Z., and R.N.W.), Hamilton Glaucoma Center, Shiley Eye Institute, University of California San Diego, La Jolla, California, USA. Electronic address: rweinreb@ucsd.edu.

Funding

Vision BiostatisticsP30EY022589 · NEI · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI Radha Ayyagari · 2012 to 2026
$10.3M
Diagnostic Innovations in Glaucoma:Structural AssessmentR01EY011008 · NEI · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI ZANGWILL, LINDA M · 1995 to 2015
$8.7M
Diagnostic Innovations in Glaucoma Study (DIGS): High Myopia and Advanced DiseaseR01EY027510 · NEI · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI LINDA M ZANGWILL · 2017 to 2026
$5.3M
Diagnosis and Monitoring of Glaucoma with Optical Coherence Tomography AngiographyR01EY029058 · NEI · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI WEINREB, ROBERT N · 2018 to 2024
$4.2M
African Descent and Glaucoma Evaluation (ADAGES) II: Glaucoma ProgressionR01EY019869 · NEI · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI ZANGWILL, LINDA M · 2010 to 2014
$2.8M
African Descent and Glaucoma Evaluation (ADAGES) IV: Alterations of the lamina cribrosa in progressionR01EY026574 · NEI · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI FAZIO, MASSIMO ANTONIO, GIRKIN, CHRISTOPHER ANTHONY · 2017 to 2020
$2.6M
Monitoring of Glaucoma Patients in Advanced DiseaseR01EY034148 · NEI · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI Sasan Moghimi Araghi · 2022 to 2026
$2.5M
NEI NIH HHS P30 EY022589NEI NIH HHS R01 EY011008NEI NIH HHS R01 EY019869NEI NIH HHS R01 EY026574NEI NIH HHS R01 EY027510NEI NIH HHS R01 EY029058NEI NIH HHS R01 EY034148
6 · The paper itself

Abstract

purposeTo determine the impact of progression of central visual field (VF) and global VF on vision-related quality of life (VRQOL).

designRetrospective cohort study.

methodsThis study included 364 eyes of 235 primary open-angle glaucoma participants who had at least five 24-2 VF tests over a minimum of 2-year follow-up. The slopes of global mean deviation (MD) and central mean total deviation (MTD

resultsThe baseline 24-2 VF MD of all participants was -5.6 (95% CI -6.4, -4.9) decibels (dB). At baseline, eyes with MTD

conclusionsCentral VF change had a greater impact on VRQOL compared to global VF change. Conventional assessments based on global MD may underestimate the effect of central VF changes. Refining progression detection strategies to include central VF is necessary to better reflect changes in patient-centered outcomes like VRQOL.

Indexed as

Glaucoma, Open-AngleQuality of LifeVision DisordersVisual FieldsAgedDisease ProgressionFemaleFollow-Up StudiesHumansIntraocular PressureMaleMiddle AgedRetrospective StudiesSickness Impact ProfileSurveys and QuestionnairesVisual Acuity

Identifiers

PMID40334725
PMCPMC13592717

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.