Evidence map›Paper›PMID 40334653›Full record

ArticleChemMedChem2025

Synthesis and Biological Evaluation of Bicyclic Pyrazolines with Promising Antimicrobial Activities.

Debora Caviglia, Anna Maria Schito, Susanna Penco, Chiara Brullo, Marcus Baumann

Abstract read
In one paragraph

Article in ChemMedChem, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Debora CavigliaDepartment of Surgical Sciences and Integrated Diagnostics, University of Genova, Viale Benedetto XV, 6, 16132, Genoa, Italy.
Anna Maria SchitoDepartment of Surgical Sciences and Integrated Diagnostics, University of Genova, Viale Benedetto XV, 6, 16132, Genoa, Italy.
Susanna PencoDepartment of Experimental Medicine, University of Genova, Via L.B. Alberti, 2, 16132, Genoa, Italy.
Chiara BrulloDepartment of Pharmacy, Section of Medicinal Chemistry, University of Genova, Viale Benedetto XV, 3, 16132, Genoa, Italy.ORCID https://orcid.org/0000-0002-2575-7726
Marcus BaumannSchool of Chemistry, University College Dublin, Science Centre South, Belfield, Dublin, Ireland.ORCID https://orcid.org/0000-0002-6996-5893

Funding

Science Foundation Ireland 12/RC2275_P2Science Foundation Ireland 19/IFA/7420Science Foundation Ireland 20/FFP-P/8712
6 · The paper itself

Abstract

The efficient photochemical synthesis of bicyclic pyrazolines using flow technology as well as the subsequent antimicrobial evaluation of these scaffolds is reported. Low minimal inhibitory concentration values of 0.5-4 μg mL

Indexed as

Anti-Bacterial AgentsPyrazolesAnimalsDose-Response Relationship, DrugEnterococcusHumansMicrobial Sensitivity TestsMolecular StructureStaphylococcusStructure-Activity RelationshipAnti-Bacterial AgentsPyrazolesantimicrobial resistancesbacteriostatic propertiesdrug‐likeness propertiesflow synthesesphoto‐click reactionspyrazolines

Identifiers

PMID40334653
PMCPMC12276031

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.