Evidence map›Paper›PMID 40334220›Full record

ArticlePLOS global public health2025

AD-AutoGPT: An autonomous GPT for Alzheimer's disease infodemiology.

Haixing Dai, Yiwei Li, Zhengliang Liu, Lin Zhao, Zihao Wu, Suhang Song, Shen Ye, Dajiang Zhu, Xiang Li, Sheng Li and 8 more

Abstract read
In one paragraph

Article in PLOS global public health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
  2. Article
  3. Advances in artificial intelligence for neuroimaging.Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2026
    Review
  4. AD-GPT: large language models in Alzheimer's disease.BMC medical informatics and decision making · 2026
    Article
  5. Large language models for bioinformatics.Quantitative biology (Beijing, China) · 2026
    Review
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors.

Haixing DaiSchool of Computing, University of Georgia, Athens, Georgia, United States of America.ORCID https://orcid.org/0000-0003-0409-6129
Yiwei LiSchool of Computing, University of Georgia, Athens, Georgia, United States of America.
Zhengliang LiuSchool of Computing, University of Georgia, Athens, Georgia, United States of America.
Lin ZhaoSchool of Computing, University of Georgia, Athens, Georgia, United States of America.
Zihao WuSchool of Computing, University of Georgia, Athens, Georgia, United States of America.
Suhang SongCollege of Public Health, University of Georgia, Athens, Georgia, United States of America.ORCID https://orcid.org/0000-0003-1934-632X
Shen YeDepartment of Epidemiology and Biostatistics, University of Georgia, Athens, Georgia, United States of America.
Dajiang ZhuDepartment of Computer Science and Engineering, University of Texas at Arlington, Arlington, Texas, United States of America.
Xiang LiMassachusetts General Hospital, Boston, Massachusetts, United States of America.ORCID https://orcid.org/0000-0002-9851-6376
Sheng LiSchool of Data Science, University of Virginia, Charlottesville, Virginia, United States of America.
Xiaobai YaoDepartment of Geography, University of Georgia, Athens, Georgia, United States of America.
Lu ShiDepartment of Public Health Science, Clemson University, Clemson, South Carolina, United States of America.
Tai-Quan PengDepartment of Communication, Michigan State University, East Lansing, Michigan, United States of America.ORCID https://orcid.org/0000-0002-2588-7491
Quanzheng LiMassachusetts General Hospital, Boston, Massachusetts, United States of America.
Zhuo ChenCollege of Public Health, University of Georgia, Athens, Georgia, United States of America.ORCID https://orcid.org/0000-0002-5351-3489
Donglan ZhangNYU Long Island School of Medicine, New York University, Mineola, New York, United States of America.
Tianming LiuSchool of Computing, University of Georgia, Athens, Georgia, United States of America.
Gengchen MaiDepartment of Geography, University of Georgia, Athens, Georgia, United States of America.ORCID https://orcid.org/0000-0002-7818-7309

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In this pioneering study, inspired by AutoGPT, the state-of-the-art open-source application based on the GPT-4 large language model, we develop a novel tool called AD-AutoGPT, which can conduct data collection, processing, and analysis about complex health narratives of Alzheimer's Disease in an autonomous manner via users' textual prompts. We collated comprehensive data from a variety of news sources, including the Alzheimer's Association, BBC, Mayo Clinic, and the National Institute on Aging since June 2022, leading to the autonomous execution of robust trend analyses, intertopic distance map visualization, and identification of salient terms pertinent to Alzheimer's Disease. This approach has yielded not only a quantifiable metric of relevant discourse but also valuable insights into public focus on Alzheimer's Disease. This application of AD-AutoGPT in public health signifies the transformative potential of AI in facilitating a data-rich understanding of complex health narratives like Alzheimer's Disease in an autonomous manner, setting the groundwork for future AI-driven investigations in global health landscapes. Code, a demo video, and other information are available at https://github.com/levyisthebest/AD-AutoGPT.

Identifiers

PMID40334220
PMCPMC12058166

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.