Evidence map›Paper›PMID 40333874›Full record

ArticlePloS one2025

Immunization status of children with cerebral palsy: A cross-sectional hospital-based study in Vietnam.

Thi Hong Hanh Khuc, Tasneem Karim, Minh Chau Cao, Thi Van Anh Nguyen, Thi Huong Giang Nguyen, Quang Dung Trinh, Rachael Dossetor, Van Bang Nguyen, Nadia Badawi, Lal Rawal and 2 more

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Article in PloS one, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Thi Hong Hanh KhucSchool of Health, Medical and Applied Sciences, Central Queensland University, Rockhampton, Queensland, Australia.ORCID https://orcid.org/0000-0002-9421-5517
Tasneem KarimCerebral Palsy Alliance Research Institute, Specialty of Child & Adolescent Health, Faculty of Medicine and Health, The University of Sydney, Sydney, New South Wales, Australia.
Minh Chau CaoFaculty of Medical Technology, Phenikaa University, Hanoi, Vietnam.
Thi Van Anh NguyenMedical Education and Skills Laboratory Department, Hanoi Medical University, Hanoi, Vietnam.
Thi Huong Giang NguyenRehabilitation Department, National Children's Hospital, Hanoi, Vietnam.
Quang Dung TrinhRehabilitation Department, National Children's Hospital, Hanoi, Vietnam.
Rachael DossetorChildren's Hospital Westmead Clinical School, Specialty of Child and Adolescent Health, Faculty of Medicine and Health, The University of Sydney, Sydney, New South Wales, Australia.
Van Bang NguyenPediatric Department, Medical Faculty, Phenikaa University, Hanoi, Vietnam.
Nadia BadawiCerebral Palsy Alliance Research Institute, Specialty of Child & Adolescent Health, Faculty of Medicine and Health, The University of Sydney, Sydney, New South Wales, Australia.
Lal RawalSchool of Health, Medical and Applied Sciences, Central Queensland University, Rockhampton, Queensland, Australia.
Gulam KhandakerSchool of Health, Medical and Applied Sciences, Central Queensland University, Rockhampton, Queensland, Australia.
Elizabeth Jane ElliottChildren's Hospital Westmead Clinical School, Specialty of Child and Adolescent Health, Faculty of Medicine and Health, The University of Sydney, Sydney, New South Wales, Australia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimTo describe the immunization status of children with CP in Vietnam and identify factors associated with vaccine non-uptake in this group.

methodsWe conducted an active prospective case ascertainment of children with cerebral palsy (CP) attending the National Children's Hospital in Hanoi between June to November 2017, following the model proposed by the Paediatric Active Enhanced Disease Surveillance system in Australia. All children were assessed by trained paediatricians at the hospital and their immunization history was recorded.

resultsData were collected from 765 children with CP (median age = 1.7 years, IQR = 2.7 years). Of these children, 82.7% were fully immunized for their age (compared to 96.4% of the general child population) according to the Vietnamese Expanded Programme on Immunization (EPI) schedule. A BCG vaccination scar was present in 94.0% of children with CP, and 95.9% of eligible children had received the measles-rubella vaccine as part of the national campaign (compared with 96.0% and 98.2% of the general population respectively). Incomplete vaccination according to the EPI was associated with younger age, living in an earth/sand house, homebirth, low-level maternal education, being diagnosed with CP before the age of three, having bilateral CP, having associated impairments (i.e., epilepsy, intellectual, visual, speech), being at level IV-V on the Gross Motor Function Classification System, and being undernutrition.

conclusionThis is the first study to document the immunization status of children with CP in Vietnam. A large proportion had not received the measles-rubella vaccine and 17.3% were not fully immunized. To increase vaccination coverage, interventions and strategies are required to ensure that all children with CP have equitable access to early diagnosis, immunization, health education programs, outreach programs, and frequent follow-up. Early diagnosis and focused intervention in early life could further improve vaccination coverage in children with CP.

Indexed as

Cerebral PalsyImmunizationVaccinationChildChild, PreschoolCross-Sectional StudiesFemaleHospitalsHumansImmunization ProgramsInfantMaleProspective StudiesVietnam

Identifiers

PMID40333874
PMCPMC12057921

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