Evidence map›Paper›PMID 40333852›Full record

ArticleMolecules (Basel, Switzerland)2025

In Vitro Evaluation of Novel Furo[3,2-

Mariagrazia Rullo, Alice Benzi, Lara Bianchi, Massimo Maccagno, Guglielmo Marcantoni Taddei, Daniela Valeria Miniero, Giuseppe Felice Mangiatordi, Giovanni Lentini, Leonardo Pisani, Giovanni Petrillo and 1 more

Abstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Mariagrazia RulloDepartment of Pharmacy-Pharmaceutical Sciences, University of Bari "Aldo Moro", Via E. Orabona, 4, 70125 Bari, Italy.ORCID 0000-0001-5304-6764
Alice BenziDepartment of Chemistry and Industrial Chemistry (DCCI), University of Genova, Via Dodecaneso 31, 16146 Genova, Italy.
Lara BianchiDepartment of Chemistry and Industrial Chemistry (DCCI), University of Genova, Via Dodecaneso 31, 16146 Genova, Italy.ORCID 0000-0001-8348-1361
Massimo MaccagnoDepartment of Chemistry and Industrial Chemistry (DCCI), University of Genova, Via Dodecaneso 31, 16146 Genova, Italy.ORCID 0000-0002-3149-4336
Guglielmo Marcantoni TaddeiDepartment of Chemistry and Industrial Chemistry (DCCI), University of Genova, Via Dodecaneso 31, 16146 Genova, Italy.
Daniela Valeria MinieroDepartment of Medicine & Surgery, LUM University Giuseppe Degennaro Torre Rossi, 70010 Puglia, Italy.ORCID 0000-0002-3324-9692
Giuseppe Felice MangiatordiCNR, Institute of Crystallography, 70126 Bari, Italy.
Giovanni LentiniDepartment of Pharmacy-Pharmaceutical Sciences, University of Bari "Aldo Moro", Via E. Orabona, 4, 70125 Bari, Italy.ORCID 0000-0001-7079-5994
Leonardo PisaniDepartment of Pharmacy-Pharmaceutical Sciences, University of Bari "Aldo Moro", Via E. Orabona, 4, 70125 Bari, Italy.ORCID 0000-0002-4198-3897
Giovanni PetrilloDepartment of Chemistry and Industrial Chemistry (DCCI), University of Genova, Via Dodecaneso 31, 16146 Genova, Italy.ORCID 0000-0002-8182-0144
Cinzia TavaniDepartment of Chemistry and Industrial Chemistry (DCCI), University of Genova, Via Dodecaneso 31, 16146 Genova, Italy.ORCID 0000-0003-4437-1121

Funding

University of Genoa Impact Boosting 2022 (DCCI)
6 · The paper itself

Abstract

Coumarin represents a privileged structural motif that is quite common in nature-derived and synthetic bioactive molecules. Some of us have recently described the straightforward preparation of complex furo[3,2-

Indexed as

Cholinesterase InhibitorsCoumarinsMonoamine OxidaseMonoamine Oxidase InhibitorsAcetylcholinesteraseButyrylcholinesteraseCell Line, TumorHumansKineticsMolecular Docking SimulationMolecular StructureStructure-Activity RelationshipAcetylcholinesteraseButyrylcholinesteraseCholinesterase InhibitorsCoumarinsMonoamine OxidaseMonoamine Oxidase Inhibitorsacetylcholinesterasebutyrylcholinesterasecytotoxicitydocking simulationsenzyme inhibitorsfuro[3,2-c]coumarinsmonoamine oxidases

Identifiers

PMID40333852
PMCPMC12029227

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.