Evidence map›Paper›PMID 40333700›Full record

ArticlePloS one2025

Urban environmental noise and depression causal pathway: Potential role of chronic conditions as mediator.

Enrique Sanz Olea, Jesus León Hernández, Begoña Artíñano, Verónica Briz, Spyros Karakitsios, Dimosthenis Sarigiannis, Saul García Dos Santos, Beatriz Nuñez-Corcuera, Rebeca Ramis

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In one paragraph

Article in PloS one, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Enrique Sanz OleaHospital Universitario La Paz, Madrid, Spain.
Jesus León HernándezHospital General Universitario de Ciudad Real, Ciudad Real, Spain.
Begoña ArtíñanoEnvironment Department, CIEMAT, Madrid, Spain.
Verónica BrizViral Hepatitis Reference and Research Laboratory, National Center of Microbiology, Institute of Health Carlos III, Madrid, Spain.
Spyros KarakitsiosHERACLES Research Center - KEDEK, Aristotle University of Thessaloniki, Thessaloniki, Greece.
Dimosthenis SarigiannisHERACLES Research Center - KEDEK, Aristotle University of Thessaloniki, Thessaloniki, Greece.
Saul García Dos SantosArea de Contaminación Atmosférica, Centro Nacional de Sanidad Ambiental, Instituto de Salud Carlos III, Madrid, Spain.
Beatriz Nuñez-CorcueraArea de Contaminación Atmosférica, Centro Nacional de Sanidad Ambiental, Instituto de Salud Carlos III, Madrid, Spain.
Rebeca RamisCancer and Environmental Epidemiology Unit, National Centre for Epidemiology, Instituto de Salud Carlos III, Madrid, Spain.ORCID https://orcid.org/0000-0001-6154-9142

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAccepting the fact of a growing urban population and associated health risks, such as increased exposure to pollutants, and considering the high prevalence of chronic diseases, this study aims to investigate the relationship between exposure to environmental noise and depression. The primary objective is to determine the potential mediating role of chronic diseases in this relationship. This study is part of the European H2020 URBANOME project, designed to explore the relationship between the environment and health in urban settings. The main goal of the project is to promote urban health, well-being, and liveability by systematically integrating health concerns into urban policies and civic activities. MATERIALS AND

methodsWe obtained the data for this study from the Madrid City Health Survey, conducted through computer-assisted telephone interviews. Outcome variables assessed through self-reports included depression, exposure to environmental noise, and the presence of chronic diseases. We used a counterfactual mediation framework, implemented by the R package multimediate, to evaluate the potential mediating role of chronic diseases in the relationship between exposure to environmental noise and depression.

resultsThe study included 8,445 interviews, with a higher percentage of women (54.67%) than men. 23.29% were over 65, and 17.17% under 30. Notably, 7.82% reported depression, 39.53% had chronic diseases, and 35.43% acknowledged noise exposure. In our regression models, those exposed to environmental noise were 1.24 times more likely to have a chronic disease, and individuals with a chronic disease were 2.93 times more likely to suffer from depression. Participants exposed to environmental noise had 1.03 times more depression, being the 13% of the noise health effect mediated by the presence of chronic illness.

conclusionOur findings suggest a link between environmental noise exposure and depression, potentially mediated by chronic diseases. This points out the need for public health interventions to reduce urban noise exposure and improve mental health. Furthermore, prospective studies are needed for confirmation, incorporating noise level measurements and temporal data on the onset of chronic diseases and depression.

Indexed as

DepressionEnvironmental ExposureNoiseAdultAgedChronic DiseaseFemaleHumansMaleMiddle AgedSpainUrban PopulationYoung Adult

Identifiers

PMID40333700
PMCPMC12057972

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.