Evidence map›Paper›PMID 40333624›Full record

ArticleMolecules (Basel, Switzerland)2025

Physicochemical and Biological Properties of Menthol and Thymol-Based Natural Deep Eutectic Solvents.

Martina Bagović Kolić, Martina Železnjak, Ksenija Markov, Višnja Gaurina Srček, Marina Cvjetko Bubalo, Kristina Radošević, Ivana Radojčić Redovniković

Abstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Martina Bagović KolićLaboratory for Cell Technology, Application and Biotransformations, Department of Biochemical Engineering, Faculty of Food Technology and Biotechnology, University of Zagreb, 10000 Zagreb, Croatia.
Martina ŽeleznjakLaboratory for Cell Technology, Application and Biotransformations, Department of Biochemical Engineering, Faculty of Food Technology and Biotechnology, University of Zagreb, 10000 Zagreb, Croatia.ORCID 0009-0009-3930-3336
Ksenija MarkovLaboratory for General Microbiology and Food Microbiology, Department of Biochemical Engineering, Faculty of Food Technology and Biotechnology, University of Zagreb, 10000 Zagreb, Croatia.ORCID 0000-0003-2259-2708
Višnja Gaurina SrčekLaboratory for Cell Technology, Application and Biotransformations, Department of Biochemical Engineering, Faculty of Food Technology and Biotechnology, University of Zagreb, 10000 Zagreb, Croatia.ORCID 0000-0001-6591-3810
Marina Cvjetko BubaloLaboratory for Cell Technology, Application and Biotransformations, Department of Biochemical Engineering, Faculty of Food Technology and Biotechnology, University of Zagreb, 10000 Zagreb, Croatia.
Kristina RadoševićLaboratory for Cell Technology, Application and Biotransformations, Department of Biochemical Engineering, Faculty of Food Technology and Biotechnology, University of Zagreb, 10000 Zagreb, Croatia.ORCID 0000-0001-5156-1893
Ivana Radojčić RedovnikovićLaboratory for Cell Technology, Application and Biotransformations, Department of Biochemical Engineering, Faculty of Food Technology and Biotechnology, University of Zagreb, 10000 Zagreb, Croatia.

Funding

Croatian Science Foundation IP-2019-04-7712
6 · The paper itself

Abstract

Seven hydrophobic deep eutectic solvents (hDESs) were characterised to evaluate their potential applicability in different industries and their environmental impact. Standard physicochemical properties were determined, yielding polarity and density values that were slightly higher for thymol-based hDESs than menthol-based ones, whereas for viscosity, the trend was opposite. Regarding biologically relevant activities, the antioxidative capacity and antimicrobial activity of hDESs were determined. Thymol-based hDESs are more potent as potential antioxidants, especially the one with coumarin as a hydrogen bond acceptor, which had the highest Oxygen Radical Absorbance Capacity (ORAC) value. Antimicrobial activity was assessed on four bacterial strains and one yeast strain. Calculated minimal inhibitory concentrations (MICs) showed that all hDESs possess this activity, and even the antimycotic effect against

Indexed as

Deep Eutectic SolventsMentholThymolAnti-Infective AgentsAntioxidantsCaco-2 CellsCandida albicansHeLa CellsHumansMicrobial Sensitivity TestsSolventsAnti-Infective AgentsAntioxidantsDeep Eutectic SolventsMentholSolventsThymolantimicrobial activityantioxidative capacityhydrophobic DESin vitro cytocompatibilityphysiochemical propertiesphytotoxicity

Identifiers

PMID40333624
PMCPMC12029795

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.