Evidence map›Paper›PMID 40333429›Full record

ArticleAnesthesia and analgesia2026

Patient- and Institution-Level Factors Associated With Intraoperative Cardiac Arrest During Major Noncardiac Surgery.

Shamieh Banihani, Troy N Coaston, Vikram Fielding-Singh, Esteban Aguayo, Joseph S Meltzer, Peyman Benharash

Abstract read
In one paragraph

Article in Anesthesia and analgesia, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Shamieh BanihaniFrom the Cardiovascular Outcomes Research Laboratories (CORELAB), David Geffen School of Medicine, University of California, Los Angeles (UCLA), Los Angeles, California.
Troy N CoastonFrom the Cardiovascular Outcomes Research Laboratories (CORELAB), David Geffen School of Medicine, University of California, Los Angeles (UCLA), Los Angeles, California.
Vikram Fielding-SinghDivision of Cardiovascular and Thoracic Anesthesia, Department of Anesthesiology, Perioperative and Pain Medicine, Stanford University School of Medicine, Stanford, California.
Esteban AguayoFrom the Cardiovascular Outcomes Research Laboratories (CORELAB), David Geffen School of Medicine, University of California, Los Angeles (UCLA), Los Angeles, California.
Joseph S MeltzerDivision of Critical Care Medicine, Department of Anesthesiology and Perioperative Medicine, University of California, Los Angeles (UCLA), Los Angeles, California.
Peyman BenharashFrom the Cardiovascular Outcomes Research Laboratories (CORELAB), David Geffen School of Medicine, University of California, Los Angeles (UCLA), Los Angeles, California.

Funding

Toward optimizing dialysis in the perioperative periodK23DK138312 · NIDDK · STANFORD UNIVERSITY · PI Vikram Fielding-Singh · 2024 to 2026
$496k
American Heart Association-American Stroke Association 23CDA1053913NIDDK NIH HHS K23 DK138312
6 · The paper itself

Abstract

backgroundIntraoperative cardiac arrest (IOCA) is a rare but catastrophic event with significant morbidity, mortality, and health care costs. This study aimed to characterize the frequency, risk factors, and outcomes of IOCA.

methodsAdults undergoing noncardiac surgery were identified in the 2016 to 2021 National Inpatient Sample. IOCA events were identified using the relevant International Classification of Diseases code. Multivariable regression models examined factors independently associated with IOCA and in-hospital mortality. The significance of temporal trends was calculated using Cuzick's nonparametric test.

resultsAmong 2671,834 noncardiac surgical admissions, 1294 (0.05%) experienced IOCA. The incidence increased from 0.05% to 0.06% during the study period, coinciding with an increase in nonelective operations during the coronavirus disease-2019 (COVID-19) pandemic. IOCA was associated with a 39.3% in-hospital mortality rate and increases in length of stay and hospitalization costs. Key risk factors for IOCA included advanced age, male sex, Black race (adjusted odds ratio [AOR] 1.40, 95% CI, 1.20-1.65), low-income status (AOR 1.21, 95% CI, 1.02-1.43), treatment at government nonfederal hospitals (AOR 1.22, 95% CI, 1.08-1.50), high-risk surgical procedures, and significant comorbidities such as congestive heart failure, cardiac arrhythmias, and valvular disease.

conclusionsDespite the initial reduction in the incidence of IOCA, this study highlights a temporal increase coinciding with the COVID-19 pandemic and an increase in nonelective surgeries. Future research should explore more granular predictors of IOCA and its outcomes to develop targeted interventions for at-risk populations and tailor guidelines to manage emerging challenges in population health.

Indexed as

Heart ArrestIntraoperative ComplicationsSurgical Procedures, OperativeAdultAgedAged, 80 and overCOVID-19FemaleHospital MortalityHumansIncidenceLength of StayMaleMiddle AgedRetrospective StudiesRisk Assessment

Identifiers

PMID40333429
PMCPMC12922580

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.