Evidence map›Paper›PMID 40333272›Full record

ArticleMaterials (Basel, Switzerland)2025

Efficacy of Three-Dimensional Bioactive Composites in Long Bone Repair with Photobiomodulation.

Sebastião Júlio Rodrigues Júnior, Letícia Carlucci Dos Santos, Daniela Vieira Buchaim, Marco Antonio Hungaro Duarte, Murilo Priori Alcalde, Benedito Barraviera, Rui Seabra Ferreira Júnior, Ana Maria de Guzzi Plepis, Virgínia da Conceição Amaro Martins, Paulo Sérgio da Silva Santos and 3 more

Abstract read
In one paragraph

Article in Materials (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Photokinetics of Mixtures of Independent Photoreactions.Molecules (Basel, Switzerland) · 2025
    Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Sebastião Júlio Rodrigues JúniorPostgraduate Program in Structural and Functional Interactions in Rehabilitation, University of Marilia (UNIMAR), Marilia 17525-902, Brazil.
Letícia Carlucci Dos SantosPostgraduate Program in Structural and Functional Interactions in Rehabilitation, University of Marilia (UNIMAR), Marilia 17525-902, Brazil.
Daniela Vieira BuchaimMedical School, University Center of Adamantina (FAI), Adamantina 17800-000, Brazil.ORCID 0000-0002-9914-1262
Marco Antonio Hungaro DuarteDepartment of Dentistry, Endodontics and Dental Materials, Bauru School of Dentistry, University of São Paulo (FOB/USP), Bauru 17012-901, Brazil.ORCID 0000-0003-3051-737X
Murilo Priori AlcaldeDepartment of Dentistry, Endodontics and Dental Materials, Bauru School of Dentistry, University of São Paulo (FOB/USP), Bauru 17012-901, Brazil.
Benedito BarravieraCenter for the Study of Venoms and Venomous Animals (CEVAP), São Paulo State University (Univ Estadual Paulista, UNESP), Botucatu 18610-307, Brazil.ORCID 0000-0002-9855-5594
Rui Seabra Ferreira JúniorCenter for the Study of Venoms and Venomous Animals (CEVAP), São Paulo State University (Univ Estadual Paulista, UNESP), Botucatu 18610-307, Brazil.ORCID 0000-0001-6952-0512
Ana Maria de Guzzi PlepisSão Carlos Institute of Chemistry, University of São Paulo (USP), São Carlos 13566-590, Brazil.ORCID 0000-0002-4360-8433
Virgínia da Conceição Amaro MartinsSão Carlos Institute of Chemistry, University of São Paulo (USP), São Carlos 13566-590, Brazil.
Paulo Sérgio da Silva SantosDepartment of Surgery, Stomatology, Pathology and Radiology, Bauru School of Dentistry, University of São Paulo (USP), Bauru 17012-901, Brazil.ORCID 0000-0002-0674-3759
Marcelo Rodrigues da CunhaPostgraduate Program in Health Sciences, Faculty of Medicine of Jundiaí (FMJ), Jundiaí 13202-550, Brazil.ORCID 0000-0002-4551-7180
Rogerio Leone BuchaimGraduate Program in Anatomy of Domestic and Wild Animals, Faculty of Veterinary Medicine and Animal Science, University of São Paulo (FMVZ/USP), São Paulo 05508-270, Brazil.ORCID 0000-0002-5881-2218
Karina Torres PominiPostgraduate Program in Structural and Functional Interactions in Rehabilitation, University of Marilia (UNIMAR), Marilia 17525-902, Brazil.ORCID 0000-0003-2858-4717

Funding

CNPq (The National Council for Scientific and Technological Development/Conselho Nacional de Desenvolvimento Científico e Tecnológico) PQ1C No. 303224/2018-5.CNPq (The National Council for Scientific and Technological Development/Conselho Nacional de Desenvolvimento Científico e Tecnológico) PQ2 No. 306339/2020-0Coordenação de Aperfeicoamento de Pessoal de 637 Nivel Superior-Brasil (CAPES) 001
6 · The paper itself

Abstract

Different treatments have been proposed for morphofunctional bone repair; however, they are not always efficient and have limitations. In this experimental study, we present matrix composites with a possible synergistic effect acting with scaffolds for bone growth and use of photobiomodulation (PBM) to accelerate this tissue repair. Thus, the objective was to evaluate the effect of PBM in the repair of a long bone (tibia) of rats filled with biomimetic collagen matrices with nanohydroxyapatite and heterologous fibrin biopolymer (FB). Forty-eight rats were distributed into eight groups (

Indexed as

bone substitutesfibrinfibrin biopolymerfibrin sealanthydroxyapatitelow-level laser therapynanohydroxyapatitephotobiomodulationregenerative medicinescaffolds

Identifiers

PMID40333272
PMCPMC12028516

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.