Evidence map›Paper›PMID 40333267›Full record

ArticleVaccines2025

A Phase 1/2 Randomized Study to Evaluate the Safety, Tolerability, and Immunogenicity of Nucleoside-Modified Messenger RNA Influenza Vaccines in Healthy Adults.

Angela Branche, Mark J Mulligan, Alok Maniar, Orlando Puente, Islamiat Oladipupo, Graham Crowther, Agnieszka M Zareba, Zhuobiao Yi, Ingrid Scully, Emily Gomme and 6 more

Abstract read
In one paragraph

Article in Vaccines, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. mRNA Vaccines for Influenza: Hope for a Universal Vaccine?BioDrugs : clinical immunotherapeutics, biopharmaceuticals and gene therapy · 2026
    Review
  3. Review
  4. Review
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Angela BrancheDepartment of Medicine, Division of Infectious Diseases, University of Rochester, Rochester, NY 14642, USA.
Mark J MulliganNew York University (NYU) Vaccine Center, NYU Grossman School of Medicine, New York, NY 10016, USA.
Alok ManiarVaccine Research and Development, Pfizer Inc., Pearl River, NY 10965, USA.ORCID 0009-0000-7366-3081
Orlando PuenteMiami Dade Medical Research Institute, Miami, FL 33176, USA.
Islamiat OladipupoVaccine Research and Development, Pfizer Inc., Pearl River, NY 10965, USA.ORCID 0000-0001-8783-403X
Graham CrowtherVaccine Research and Development, Pfizer Ltd., Hurley SL6 6RJ, UK.
Agnieszka M ZarebaVaccine Research and Development, Pfizer Inc., Collegeville, PA 19426, USA.
Zhuobiao YiVaccine Research and Development, Pfizer Inc., Collegeville, PA 19426, USA.
Ingrid ScullyVaccine Research and Development, Pfizer Inc., Pearl River, NY 10965, USA.
Emily GommeVaccine Research and Development, Pfizer Inc., Pearl River, NY 10965, USA.
Kenneth KouryVaccine Research and Development, Pfizer Inc., Pearl River, NY 10965, USA.
Nicholas KitchinVaccine Research and Development, Pfizer Ltd., Hurley SL6 6RJ, UK.ORCID 0000-0002-1808-3380
Pirada Suphaphiphat AllenVaccine Research and Development, Pfizer Inc., Pearl River, NY 10965, USA.
Annaliesa S AndersonVaccine Research and Development, Pfizer Inc., Pearl River, NY 10965, USA.
Alejandra GurtmanVaccine Research and Development, Pfizer Inc., Pearl River, NY 10965, USA.
Kelly LindertVaccine Research and Development, Pfizer Inc., Cambridge, MA 02139, USA.

Funding

Pfizer Inc N/A
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

immunogenicityinfluenzamodRNAsafetytolerabilityvaccination

Identifiers

PMID40333267
PMCPMC12031420

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.