ArticleVaccines2025
Assessing Immunization Coverage and the Negative Impact of Local Vaccine Production Cessation in Ecuador.
Article in Vaccines, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Ecuador's 2025 presidential election and the disconnection between public health and the political agendas.Frontiers in public health · 2025Article
Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe COVID-19 pandemic highlighted vaccine importance while exposing inequities in global immunization, especially in LMICs like Ecuador. Local vaccine production ensures supply, reduces reliance on imports, and boosts health security. Understanding the relationship between local production and vaccination outcomes is crucial to addressing emerging public health challenges.
objectiveThe objective was to assess the impact of local vaccine production cessation on vaccination coverage rates for BCG- and DTP-containing vaccines. METHODOLOGY: This retrospective cross-sectional study analyzed vaccine coverage data from 2004 to 2023, focusing on key vaccines such as BCG and DTP, to assess the impact of the cessation of local vaccine production. Mann-Whitney U tests were conducted to compare vaccination coverage during the periods of local production (2004-2013) and post-production cessation (2014-2023). Historical context and policy implications were also evaluated to provide a comprehensive perspective.
resultsA significant decline in vaccine coverage was observed following the cessation of local production. For BCG, median coverage decreased from 100% during the production period to 87.8% post-cessation (
conclusionsReinvesting in local vaccine production is pivotal to improving immunization outcomes and strengthening Ecuador's health security. International collaboration and strategic planning can help overcome current challenges, positioning Ecuador as a regional leader in vaccine production and public health resilience.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.