Evidence map›Paper›PMID 40333151›Full record

ArticlePathogens (Basel, Switzerland)2025

The Epidemiology of Respiratory Syncytial Virus and the Impact of the COVID-19 Pandemic in a Retrospective Evaluation.

Paolo Solidoro, Antonio Curtoni, Cristina Costa, Francesco Giuseppe De Rosa, Alessandro Bondi, Francesca Sidoti, Nour Shbaklo, Filippo Patrucco, Davide Favre, Elisa Zanotto and 2 more

Abstract read
In one paragraph

Article in Pathogens (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Paolo SolidoroDivision of Respiratory Medicine, Cardiovascular and Thoracic Department, AOU Città Della Salute e Della Scienza di Torino, University of Turin, 10126 Torino, Italy.ORCID 0000-0003-3972-2871
Antonio CurtoniDivision of Virology, Department of Public Health and Pediatrics, AOU Città Della Salute e Della Scienza di Torino, University of Turin, 10126 Torino, Italy.ORCID 0000-0001-8101-4196
Cristina CostaDivision of Virology, Department of Public Health and Pediatrics, AOU Città Della Salute e Della Scienza di Torino, University of Turin, 10126 Torino, Italy.ORCID 0000-0002-6549-4553
Francesco Giuseppe De RosaDepartment of Medical Sciences, Unit of Infectious Diseases, University of Turin, 10149 Torino, Italy.ORCID 0000-0001-8338-0130
Alessandro BondiDivision of Virology, Department of Public Health and Pediatrics, AOU Città Della Salute e Della Scienza di Torino, University of Turin, 10126 Torino, Italy.ORCID 0000-0002-1979-3229
Francesca SidotiDivision of Virology, Department of Public Health and Pediatrics, AOU Città Della Salute e Della Scienza di Torino, University of Turin, 10126 Torino, Italy.ORCID 0000-0001-5241-5273
Nour ShbakloDepartment of Medical Sciences, Unit of Infectious Diseases, University of Turin, 10149 Torino, Italy.
Filippo PatruccoRespiratory Diseases Unit, Medical Department, AOU Maggiore Della Carità di Novara, 28100 Novara, Italy.
Davide FavreDivision of Respiratory Medicine, Cardiovascular and Thoracic Department, AOU Città Della Salute e Della Scienza di Torino, University of Turin, 10126 Torino, Italy.
Elisa ZanottoDivision of Virology, Department of Public Health and Pediatrics, AOU Città Della Salute e Della Scienza di Torino, University of Turin, 10126 Torino, Italy.
Silvia CorcioneDepartment of Medical Sciences, Unit of Infectious Diseases, University of Turin, 10149 Torino, Italy.
Rocco Francesco RinaldoDivision of Respiratory Medicine, Cardiovascular and Thoracic Department, AOU Città Della Salute e Della Scienza di Torino, University of Turin, 10126 Torino, Italy.ORCID 0000-0003-3999-5298

Funding

EU funding within the MUR PNRR Extended Partnership initiative on Emerging Infectious Diseases PE00000007, INF-ACT
6 · The paper itself

Abstract

introductionRespiratory syncytial virus (RSV) is the main etiological agent in pediatric lower respiratory tract infections. The limited availability of therapeutic options for severe clinical cases associated with RSV infection makes prophylactic interventions a priority for containment. The aim of the current study was to evaluate the epidemiology of RSV in the Piedmont population and the consequences of containment measures applied during the pandemic on viral circulation in the immediate and medium-term post-pandemic phase.

methodsThis study considered all biological samples analyzed for RSV at the City of Health and Science of Turin collected from 1 January 2016 to 31 December 2023. Evaluation of the positivity rates of samples was performed and differences between pediatric and adult population swabs (nasopharyngeal, pharyngeal, nasal aspirates) and bronchoalveolar samples were reported.

resultsThis study analyzed 14,085 samples and highlighted a trend in Piedmont RSV infections characterized by a higher pediatric population involvement of 82% compared to the adult population at 17%. A higher number of URT infections (95%) compared to LRT infections (4.6%) was also identified. This study shows a peak in RSV cases from November to April between 2016 and 2020. Our data show no RSV positivity during the 2020/2021 winter season, a result most likely due to the influence of containment measures implemented during the COVID-19 pandemic.

conclusionsOur study provided an epidemiological panorama of RSV and its high prevalence in pediatrics and adults. Pediatrics had a higher prevalence, while adults presented a delayed trend of about one month compared to pediatrics. The effectiveness of infection control measures applied during the SARS-CoV-2 pandemic to limit viral infections were proved. Future studies may further investigate the impact of the SARS pandemic on RSV epidemiology considering patients at a higher risk of severe symptoms.

Indexed as

COVID-19Respiratory Syncytial Virus, HumanRespiratory Syncytial Virus InfectionsAdolescentAdultAgedChildChild, PreschoolFemaleHumansInfantInfant, NewbornItalyMaleMiddle AgedPandemicsCOVID-19epidemiologypandemicrespiratory syncytial virus

Identifiers

PMID40333151
PMCPMC12030671

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.