Evidence map›Paper›PMID 40333139›Full record

ArticlePathogens (Basel, Switzerland)2025

Pregnant Women Chronically Infected by

Carolina Salomão Lopes, Ricardo José Victal Carvalho, Tamires Lopes da Silva, Heber Leão Silva Barros, Lucas Vasconcelos Soares Costa, Danielly Christine Adriani Maia Mota, Bellisa Freitas Barbosa, Luan Souza Vieira, Talyene Marques de Araújo, Alírio Resende Costa and 4 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Pathogens (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Trem2 negatively regulates the MTOR-PKCα axis to protect againstFrontiers in cellular and infection microbiology · 2026
    Article
  3. Article
  4. Beyond Latency: ChronicBiomedicines · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Carolina Salomão LopesLaboratory of Immunoparasitology, Department of Immunology, Institute of Biomedical Sciences, Federal University of Uberlândia, Uberlândia 380405-317, MG, Brazil.ORCID 0000-0002-2644-7949
Ricardo José Victal CarvalhoLaboratory of Immunoparasitology, Department of Immunology, Institute of Biomedical Sciences, Federal University of Uberlândia, Uberlândia 380405-317, MG, Brazil.
Tamires Lopes da SilvaLaboratory of Immunoparasitology, Department of Immunology, Institute of Biomedical Sciences, Federal University of Uberlândia, Uberlândia 380405-317, MG, Brazil.
Heber Leão Silva BarrosLaboratory of Immunoparasitology, Department of Immunology, Institute of Biomedical Sciences, Federal University of Uberlândia, Uberlândia 380405-317, MG, Brazil.
Lucas Vasconcelos Soares CostaLaboratory of Immunoparasitology, Department of Immunology, Institute of Biomedical Sciences, Federal University of Uberlândia, Uberlândia 380405-317, MG, Brazil.ORCID 0000-0003-3911-0672
Danielly Christine Adriani Maia MotaLaboratory of Immunoparasitology, Department of Immunology, Institute of Biomedical Sciences, Federal University of Uberlândia, Uberlândia 380405-317, MG, Brazil.ORCID 0000-0001-6142-6492
Bellisa Freitas BarbosaLaboratory of Immunophysiology of Reproduction, Institute of Biomedical Sciences, Federal University of Uberlândia, Uberlândia 380405-317, MG, Brazil.
Luan Souza VieiraClinical Department, Faculty of Medicine, Federal University of Uberlândia, Uberlândia 380405-317, MG, Brazil.
Talyene Marques de AraújoClinical Department, Faculty of Medicine, Federal University of Uberlândia, Uberlândia 380405-317, MG, Brazil.
Alírio Resende CostaClinical Department, Faculty of Medicine, Federal University of Uberlândia, Uberlândia 380405-317, MG, Brazil.
Ruth Opeyemi AwoyinkaLaboratory of Immunoparasitology, Department of Immunology, Institute of Biomedical Sciences, Federal University of Uberlândia, Uberlândia 380405-317, MG, Brazil.
Tiago Wilson Patriarca MineoLaboratory of Immunoparasitology, Department of Immunology, Institute of Biomedical Sciences, Federal University of Uberlândia, Uberlândia 380405-317, MG, Brazil.ORCID 0000-0002-2339-2743
Angélica Lemos Debs DinizGynecology and Obstetrics Department, Faculty of Medicine, Federal University of Uberlândia, Uberlândia 380405-317, MG, Brazil.
José Roberto MineoLaboratory of Immunoparasitology, Department of Immunology, Institute of Biomedical Sciences, Federal University of Uberlândia, Uberlândia 380405-317, MG, Brazil.ORCID 0000-0002-9010-7228

Funding

Conselho Nacional de Desenvolvimento Científico e Tecnológico-CNPq 312201/2021-4 and 445569/2020-4Coordenação de Aperfeiçoamento de Pessoal de Nível Superior-CAPES AUXPE-02450/09-7Fundação de Amparo à Pesquisa do Estado de Minas Gerais-FAPEMIG RED-00198-23 and APQ-01313-14
6 · The paper itself

Abstract

Depressive disorder during pregnancy is a common condition, affecting approximately 10-15% of pregnant women, and is associated with adverse pregnancy outcomes such as inadequate prenatal care, substance abuse, and fetal growth restriction. Beyond neurotransmitter disturbances, increasing evidence suggests that infectious agents may play a role in the pathophysiology of depression through immune system modulation.

Indexed as

CytokinesDepressive DisorderPregnancy Complications, InfectiousPregnancy Complications, ParasiticToxoplasmaToxoplasmosisAdolescentAdultFemaleHumansPregnancyYoung AdultCytokinesantibodieschronic infectioncytokinesdepressive disorderimmune modulationpregnancyToxoplasma gondii

Identifiers

PMID40333139
PMCPMC12030257

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.