Evidence map›Paper›PMID 40333083›Full record

ArticlePathogens (Basel, Switzerland)2025

N-Acetylcysteine as a Host-Directed Therapy Against Clarithromycin-Resistant

Shuqi Yang, Ying Zhang, Jinchuan Xu, Zhenyan Chen, Yang Ren, Yujiao Long, Xuejiao Huang, Juanxi Liu, Huan Huang, Shiqi Xie and 5 more

Abstract read
In one paragraph

Article in Pathogens (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Shuqi YangShanghai Public Health Clinical Center, Fudan University, 2901 Cao Lang Road, Jinshan District, Shanghai 201508, China.
Ying ZhangShanghai Public Health Clinical Center, Fudan University, 2901 Cao Lang Road, Jinshan District, Shanghai 201508, China.
Jinchuan XuShanghai Public Health Clinical Center, Fudan University, 2901 Cao Lang Road, Jinshan District, Shanghai 201508, China.
Zhenyan ChenShanghai Public Health Clinical Center, Fudan University, 2901 Cao Lang Road, Jinshan District, Shanghai 201508, China.
Yang RenShanghai Public Health Clinical Center, Fudan University, 2901 Cao Lang Road, Jinshan District, Shanghai 201508, China.
Yujiao LongShanghai Public Health Clinical Center, Fudan University, 2901 Cao Lang Road, Jinshan District, Shanghai 201508, China.
Xuejiao HuangShanghai Public Health Clinical Center, Fudan University, 2901 Cao Lang Road, Jinshan District, Shanghai 201508, China.
Juanxi LiuShanghai Public Health Clinical Center, Fudan University, 2901 Cao Lang Road, Jinshan District, Shanghai 201508, China.
Huan HuangShanghai Public Health Clinical Center, Fudan University, 2901 Cao Lang Road, Jinshan District, Shanghai 201508, China.
Shiqi XieShanghai Public Health Clinical Center, Fudan University, 2901 Cao Lang Road, Jinshan District, Shanghai 201508, China.
Ruiqing MaShanghai Public Health Clinical Center, Fudan University, 2901 Cao Lang Road, Jinshan District, Shanghai 201508, China.
Yajuan DongShanghai Public Health Clinical Center, Fudan University, 2901 Cao Lang Road, Jinshan District, Shanghai 201508, China.
Xiaoyong FanShanghai Public Health Clinical Center, Fudan University, 2901 Cao Lang Road, Jinshan District, Shanghai 201508, China.ORCID 0000-0001-6654-3559
Zhidong HuShanghai Public Health Clinical Center, Fudan University, 2901 Cao Lang Road, Jinshan District, Shanghai 201508, China.ORCID 0000-0001-8490-4389
Feng LiShanghai Public Health Clinical Center, Fudan University, 2901 Cao Lang Road, Jinshan District, Shanghai 201508, China.

Funding

Science and Technology Commission of Shanghai Municipality 20Z11901002Science and Technology Commission of Shanghai Municipality 21Y11901700Shanghai Municipal Science and Technology Major Project ZD2021CY001
6 · The paper itself

Abstract

(1) Background: The treatment of

Indexed as

AcetylcysteineAnti-Bacterial AgentsClarithromycinDrug Resistance, BacterialMycobacterium abscessusMycobacterium Infections, NontuberculousAnimalsDisease Models, AnimalFemaleHumansMiceSignal TransductionTHP-1 CellsAcetylcysteineAnti-Bacterial AgentsClarithromycinclarithromycinhost-directed therapyimmune regulationMycobacterium abscessusN-acetylcysteinenon-tuberculous mycobacteria

Identifiers

PMID40333083
PMCPMC12030110

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.