Evidence map›Paper›PMID 40332658›Full record

ArticleEuropean geriatric medicine2025

Medication use patterns among older patients in temporary stays in Denmark.

Hanin Harbi, Carina Lundby, Peter Bjødstrup Jensen, Søren Post Larsen, Linda Grouleff Rørbæk, Lene Vestergaard Ravn-Nielsen, Jesper Ryg, Mette Reilev, Kasper Edwards, Anton Pottegård

Abstract read
In one paragraph

Article in European geriatric medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Hanin HarbiClinical Pharmacology, Pharmacy and Environmental Medicine, Department of Public Health, University of Southern Denmark, Campusvej 55, 5230, Odense M, Denmark.ORCID http://orcid.org/0009-0004-3776-6541
Carina LundbyClinical Pharmacology, Pharmacy and Environmental Medicine, Department of Public Health, University of Southern Denmark, Campusvej 55, 5230, Odense M, Denmark.ORCID http://orcid.org/0000-0002-2121-6252
Peter Bjødstrup JensenClinical Pharmacology, Pharmacy and Environmental Medicine, Department of Public Health, University of Southern Denmark, Campusvej 55, 5230, Odense M, Denmark.ORCID http://orcid.org/0000-0001-5435-9092
Søren Post LarsenREAGENS, Skårup Fyn, Denmark.ORCID http://orcid.org/0009-0000-8854-1909
Linda Grouleff RørbækKomponent, Copenhagen, Denmark.
Lene Vestergaard Ravn-NielsenHospital Pharmacy Funen, Odense University Hospital, Odense, Denmark.ORCID http://orcid.org/0000-0001-9109-3270
Jesper RygGeriatric Research Unit, Department of Clinical Research, University of Southern Denmark, Odense, Denmark.ORCID http://orcid.org/0000-0002-8641-3062
Mette ReilevClinical Pharmacology, Pharmacy and Environmental Medicine, Department of Public Health, University of Southern Denmark, Campusvej 55, 5230, Odense M, Denmark.ORCID http://orcid.org/0000-0003-1241-4385
Kasper EdwardsDTU Engineering Technology, Technical University of Denmark, Ballerup, Denmark.ORCID http://orcid.org/0000-0002-6328-1765
Anton PottegårdClinical Pharmacology, Pharmacy and Environmental Medicine, Department of Public Health, University of Southern Denmark, Campusvej 55, 5230, Odense M, Denmark. apottegaard@health.sdu.dk.ORCID http://orcid.org/0000-0001-9314-5679

Funding

Novo Nordisk Fonden NNF22OC0077454
6 · The paper itself

Abstract

purposePatients in temporary stays are typically older individuals with frailty and multimorbidity. However, limited knowledge exists about their medication use. This study aimed to describe prescription drug use among patients in temporary stays in Denmark.

methodsWe conducted a drug utilisation study on 11,424 patients in public healthcare-operated temporary stay units across 14 Danish municipalities between 2016 and 2023 (median age 81 years; 54% women). Prescription data were sourced from the Danish National Prescription Registry.

resultsPatients used a median of six drug classes (interquartile range [IQR] 4-10) in the four months before moving into a temporary stay facility; 68% used ≥ 5 drug classes, and 26% used ≥ 10. The most commonly used drug classes were paracetamol (49%), statins (30%), and proton pump inhibitors (29%). The monthly rate of new drug use increased from 23/100 patients six months before move-in to a peak of 262/100 patients in the first month after move-in, driven primarily by laxatives, analgesics, and antibiotics. High-risk drug use increased from 70 to 83% following move-in, with 49% of patients initiating at least one new high-risk drug, most commonly opioids (28%), potassium (17%), and anticoagulants and platelet inhibitors (15%). General practitioners initiated 60-70% of treatments and maintained 80-90%. Hospital physician prescriptions increased around move-in, peaking at 55% for initiation and 25% for maintenance in the first month after move-in.

conclusionPatients in temporary stays in Denmark demonstrate high medication use, including high-risk drugs, with a notable increase in treatment initiations around the time of move-in.

Indexed as

Drug UtilizationPrescription DrugsAgedAged, 80 and overDenmarkDrug PrescriptionsFemaleHumansMalePolypharmacyRegistriesPrescription DrugsAgedDrug utilizationEpidemiologyIntermediate care facilitiesPolypharmacySkilled nursing facilities

Identifiers

PMID40332658
PMCPMC12378489

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.