Evidence map›Paper›PMID 40332643›Full record

ArticleJapanese journal of ophthalmology2025

Evaluation of changes in retinal light sensitivity thresholds in the early postoperative days after trabeculectomy using microperimetry.

Takeshi Yoshida, Sho Ogawa, Takayuki Miki, Yuiko Kodera, Gen Shimizu, Sota Yoshimoto, Keigo Sugisawa, Motohisa Ohno, Shintaro Yasuda, Yuto Shiotani and 1 more

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Article in Japanese journal of ophthalmology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

11 authors.

Takeshi YoshidaDepartment of Ophthalmology and Visual Science, Tokyo Medical and Dental University, Tokyo, Japan. takec.oph@tmd.ac.jp.
Sho OgawaDepartment of Ophthalmology and Visual Science, Tokyo Medical and Dental University, Tokyo, Japan.
Takayuki MikiDepartment of Ophthalmology and Visual Science, Tokyo Medical and Dental University, Tokyo, Japan.
Yuiko KoderaDepartment of Ophthalmology and Visual Science, Tokyo Medical and Dental University, Tokyo, Japan.
Gen ShimizuDepartment of Ophthalmology and Visual Science, Tokyo Medical and Dental University, Tokyo, Japan.
Sota YoshimotoDepartment of Ophthalmology and Visual Science, Tokyo Medical and Dental University, Tokyo, Japan.
Keigo SugisawaDepartment of Ophthalmology and Visual Science, Tokyo Medical and Dental University, Tokyo, Japan.
Motohisa OhnoDepartment of Ophthalmology and Visual Science, Tokyo Medical and Dental University, Tokyo, Japan.
Shintaro YasudaDepartment of Ophthalmology and Visual Science, Tokyo Medical and Dental University, Tokyo, Japan.
Yuto ShiotaniDepartment of Ophthalmology and Visual Science, Tokyo Medical and Dental University, Tokyo, Japan.
Kyoko Ohno-MatsuiDepartment of Ophthalmology and Visual Science, Tokyo Medical and Dental University, Tokyo, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo investigate early postoperative changes in retinal light sensitivity at the foveal and paramacular points in open angle glaucoma patients. STUDY

designRetrospective cohort study.

methodsTwenty-four eyes undergoing trabeculectomy were analyzed. Retinal light sensitivity thresholds were measured using microperimetry both before and 7 days after surgery. Linear regression analysis identified factors affecting postoperative sensitivity changes. We also evaluated the correlation between changes in the threshold of retinal light sensitivity at the foveal and paramacular points.

resultsIntraocular pressure significantly decreased postoperatively. The mean threshold values of retinal light sensitivity following surgery showed no statistically significant changes compared with preoperative values across all eyes. Specifically, the mean threshold values increased in 4 eyes, decreased in 2, and remained stable in 18. Upon analyzing each examination point, 71.8% eyes exhibited stability, 12.8% showed a decrease of less than -6 dB, and 15.4% demonstrated an improvement of more than +6 dB in threshold values of retinal light sensitivity post-surgery. Changes in retinal light sensitivity at most paramacular points were found to be independent of those at the fovea. Excessive IOP reduction was identified as a significant risk factor for central visual field impairment.

conclusionsLocalized changes in retinal light sensitivity thresholds can vary in the early postoperative period following trabeculectomy, highlighting the need to monitor localized retinal function to better understand its impact on visual outcomes.

Indexed as

Glaucoma, Open-AngleRetinaSensory ThresholdsTrabeculectomyVisual FieldsVisual Field TestsAgedFemaleFollow-Up StudiesHumansIntraocular PressureLightMaleMiddle AgedPostoperative PeriodRetrospective StudiesGlaucomaMicroperimetryPostoperative outcomeRetinal light sensitivityTrabeculectomy

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.