Evidence map›Paper›PMID 40332631›Full record

ArticleMedical & biological engineering & computing2025

Prediction of bone ingrowth into the porous swelling bone anchors using an osteoconnectivity-based adaptive finite element algorithm.

Amirreza Sadighi, Nolan Black, Mehrangiz Taheri, Moein Taghvaei, Sorin Siegler, Thomas P Schaer, Ahmad R Najafi

Abstract read
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Article in Medical & biological engineering & computing, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Amirreza SadighiDepartment of Mechanical Engineering and Mechanics, Drexel University, Philadelphia, PA, 19104, USA.
Nolan BlackDepartment of Mechanical Engineering and Mechanics, Drexel University, Philadelphia, PA, 19104, USA.
Mehrangiz TaheriDepartment of Mechanical Engineering and Mechanics, Drexel University, Philadelphia, PA, 19104, USA.
Moein TaghvaeiDepartment of Mechanical Engineering and Mechanics, Drexel University, Philadelphia, PA, 19104, USA.
Sorin SieglerDepartment of Mechanical Engineering and Mechanics, Drexel University, Philadelphia, PA, 19104, USA.
Thomas P SchaerDepartment of Clinical Studies New Bolton Center, University of Pennsylvania School of Veterinary Medicine, Philadelphia, PA, 19348, USA.
Ahmad R NajafiDepartment of Mechanical Engineering and Mechanics, Drexel University, Philadelphia, PA, 19104, USA. arn55@drexel.edu.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In this study, a bone ingrowth framework was developed, which was integrated with a hygro-elastic swelling simulation, to evaluate the ingrowth of bone into porous co-polymeric swelling bone anchors. The aim was to investigate the impact of swelling-induced radial stress on bone ingrowth and the improvement in the mechanical properties and fixation strength of the anchors. Using the finite element method coupled with the osteoconnectivity matrix, the model successfully predicted the sequential bone formation within the porous bone anchor. The bone ingrowth framework was validated based on available experimental data, closely aligning with empirical observations. The results show that owing to radial stresses generated in the bone-anchor interface by swelling, considerable bone ingrowth could be stimulated. Moreover, among the three finite element models incorporating porosity within the recommended pore size range (300-600

Indexed as

AlgorithmsBone and BonesFinite Element AnalysisSuture AnchorsBiomechanical PhenomenaComputer SimulationHumansPorosityStress, MechanicalBone ingrowthBone remodelingCo-polymeric bone anchorsHygroscopic swellingOsteointegration

Identifiers

PMID40332631
PMCPMC12436575

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.