Evidence map›Paper›PMID 40332618›Full record

ArticleBiotechnology letters2025

A new strategy for the fermentation of Massa Medicata Fermentata by combining multiple strains of fermentation and their fermentation mechanisms.

Wanqiu Liu, Ying Liu, Jie Zhang, Huangyao Zhu, Siqi Fan, Jingwen Ha, Yuxuan Lu, Yizhu Wang, Wenyuan Liu, Ma Mi and 2 more

Abstract read
PubMed Publisher
In one paragraph

Article in Biotechnology letters, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Wanqiu LiuTibetan Medicine Institute, Tibetan University of Tibetan Medicine, Lhasa, 850007, P. R. China.
Ying LiuSchool of Chinese Materia Medica, China Pharmaceutical University, Nanjing, 210009, P. R. China.
Jie ZhangSchool of Chinese Materia Medica, China Pharmaceutical University, Nanjing, 210009, P. R. China.
Huangyao ZhuSchool of Chinese Materia Medica, China Pharmaceutical University, Nanjing, 210009, P. R. China.
Siqi FanSchool of Chinese Materia Medica, China Pharmaceutical University, Nanjing, 210009, P. R. China.
Jingwen HaSchool of Chinese Materia Medica, China Pharmaceutical University, Nanjing, 210009, P. R. China.
Yuxuan LuSchool of Chinese Materia Medica, China Pharmaceutical University, Nanjing, 210009, P. R. China.
Yizhu WangSchool of Pharmacy, China Pharmaceutical University, Nanjing, 210009, P. R. China.
Wenyuan LiuSchool of Pharmacy, China Pharmaceutical University, Nanjing, 210009, P. R. China.
Ma MiTibetan Medicine Institute, Tibetan University of Tibetan Medicine, Lhasa, 850007, P. R. China.
Feng FengSchool of Pharmacy, Nanjing Medical University, Nanjing, 211166, P. R. China.
Jian XuTibetan Medicine Institute, Tibetan University of Tibetan Medicine, Lhasa, 850007, P. R. China. xujian201009@126.com.ORCID http://orcid.org/0009-0003-4384-3884

Funding

National Natural Science Foundation of China NO. 82360760
6 · The paper itself

Abstract

To address the quality instability of the traditional fermentation process of Massa Medicata Fermentata (LSQ), we designed an innovation strategy for dual-strain co-fermentation LSQ. Rhizopus arrhizus, Bacillus velezensis, Bacillus subtills, and Bacillus cereus were selected as the fermentation strains for the LSQ. After dual-strain co-fermentation, its pro-digestive enzymes and anti-inflammatory activities were significantly enhanced. Particularly, R. arrhizus/B. subtills fermentation group showed the prominent promotion of the enzymatic activities of amyloglucosidase, cellulase and trypsin, with AC200 values < 1.00 and Max fold increase values of 27.39 ± 0.22, 25.39 ± 0.87 and 48.07 ± 1.84, respectively, and anti-inflammatory activity with an IC

Indexed as

FermentationAnti-Inflammatory AgentsBacillusRhizopusAnti-Inflammatory AgentsAnti-inflammatoryBacillusCo-fermentationMassa Medicata FermentataPro-digestiveRhizopus arrhizus

Identifiers

PMID40332618

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.