ArticleSurgery today2025
Significance of Naples prognostic score for postoperative complications after colorectal cancer surgery.
Article in Surgery today, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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Who cites it
5 citing papers in PubMed.
- Minimally invasive colectomy May contribute to a better long-term prognosis for patients when a textbook outcome is not achieved.Surgery today · 2026Article
- Clinical significance of the naples prognostic score in patients with colorectal liver metastases.Surgery today · 2026Article
- Relationship between preoperative modified frailty index, immune-inflammation index, and outcomes of colorectal cancer surgery in older patients.World journal of gastrointestinal oncology · 2026Article
- Development and validation of a nomogram for predicting moderate-to-severe complications following primary tumor resection in metastatic colorectal cancer.Frontiers in oncology · 2026Article
- Combination of Naples prognostic score and pathological factors for evaluating the long-term prognosis of patients with late-onset colorectal cancer: a multicenter machine learning study.Translational cancer research · 2025Article
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Authors and funding
10 authors.
Funding
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Abstract
purposeThe Naples prognostic score (NPS) is a sensitive scoring system that reflects both inflammatory and nutritional status. This study examined the significance of NPS in predicting postoperative complications following colorectal cancer surgery.
methodsThe present study included data from 443 patients who underwent curative resection for colorectal cancer. The patients were classified into low NPS (score 0-2) and high NPS (score 3-4) groups. We retrospectively investigated the relationship between NPS and postoperative complications (Clavien-Dindo classification ≥ II).
resultsAmong all patients, 57 (13%) developed postoperative complications. A total of 340 patients (77%) were categorized into the low NPS group and 103 (23%) were categorized into the high NPS group. A multivariate analysis identified that high NPS (P < 0.001), tumor location in the rectum (P = 0.025), longer operation time (P = 0.027), and greater blood loss (P = 0.004) were independent risk factors for postoperative complications. Furthermore, high NPS was significantly associated with older age (P < 0.001), higher American Society of Anesthesiologists physical status score (P = 0.029), advanced T stage (P < 0.001), N stage (P = 0.036), and longer length of hospital stay (P < 0.010).
conclusionsNPS is a strong predictor of poor outcomes in patients undergoing curative resection for colorectal cancer, suggesting the importance of systemic inflammation and the nutritional status.
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